Naslov
Changes in uropathologic findings at a 20-year distance

Autori
Tomić, Karla ; Krajačić, Gabrijela ; Kraus, Ognjen ; Krušlin, Božo ; Belicza, Mladen

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, ostalo

Izvornik
Acta Clinica Croatica / Kusić, Zvonko - Zagreb : Birotisak, 2004, 242-242

Skup
15th "LJudevit Jurak" International Symposium on Comparative Pathology

Mjesto i datum
Zagreb, Hrvatska, 04.06.2004. - 05.06.2004

Vrsta sudjelovanja
Poster

Vrsta recenzije
Domaća recenzija

Ključne riječi
Uropathologic findings; urologic neoplasms

Sažetak
During the last 20 years, the occurrence of some diseases has changed due to a different way of living and new diagnostic and treatment possibilities. Diagnostic imaging (CT, MR and especially ultrasound) has increased the rate of identification of renal tumors, while there has not been any systematic screening for urologic diseases. Department of Urology is a referral center for prostate diseases since 1994. The procedure of needle core biopsy was introduced two years later and its utilization has increased significantly over the last few years. In the present study, the occurrence of some urologic diseases was compared at 20 years apart using the histopathologic database for 2 two-year periods. Data on all patients who underwent biopsies at Department of Urology during the 1980-1981 and 2000-2001 periods were included in the study. In the 1980/81 period, tissue samples of 25, 117 patients were analyzed at Department of Pathology, 1070 (4.3%) samples being obtained from urologic patients. In the 2000/01 period, there were 27, 720 patients, 2, 233 (8%) of them from Department of Urology. Urogenital tract tuberculosis was found in 13 (1.2%) patients during the 1980/81 period, and in only two (0.1%) patients in the 2000/01 period. In the 1980/81 and 2000/01 periods, there were 13 (1.2%) and 102 (4.6%) renal cell carcinomas, respectively. Of all urologic biopsies in the first period there was only one (0.1%) case, and in the 2000/01 period there were 17 (0.8%) cases of urothelial carcinoma of the pyelon. In the 1980/81 period there was not a single case of oncocytoma, whereas in the 2000/01 period 3 cases of oncocytoma were recorded. There were 106 (10%) and 64 (0.2%) testicular biopsies in the total number of urologic patients in the 1980/81 and 2000/01 periods, respectively. Of all testicular biopsies there were 13 (12%) and 29 (45%) tumors of the testis in the 1980/01 and 2000/01 periods, respectively. Seminoma accounted for 30% (n=4) and 55% (n=16) of all germ cell tumors in the 1980/81 and 2000/01 periods, respectively. Of the total number of urology biopsies performed in 1980/81 and 2000/01, there were 416 (38.8%) and 963 (43%) prostate biopsies, respectively, 59 (14 %) of them carcinomas in 1980/81 and 222 (23 %) carcinomas in 2000/01. An increasing number of prostate biopsies was recorded in the 2000/01 period, mainly due to the large proportion of needle core biopsies (304 of 966 prostatic biopsies). Prostatic biopsies accounted for 40% of all urologic biopsies in 2000 and for 46% in 2001. On the basis of this study it is concluded that the total number of urologic biopsies increased 1.9-fold comparing the first (1980-1981) and second (2000-2001) period. There was a significant increase in the number of renal cell carcinoma (3.8-fold) and urothelial carcinoma of the pyelon (8.4-fold). The total number of testicular biopsies decreased, whereas the number of testicular tumors and seminomas increased. Tuberculosis of the urogenital system decreased 13-fold.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti, Javno zdravstvo i zdravstvena zaštita

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