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Pregled bibliografske jedinice broj: 155420

Synthesis and Activity of Amidino Substituted 2-Phenylbenzothiazoles

Racane, Livio; Kitson, Richard P; Tralić-Kulenović, Vesna; Karminski-Zamola, Grace
Synthesis and Activity of Amidino Substituted 2-Phenylbenzothiazoles // Abstracts from the XVIII Internatinal Symposium on Medicinal Chemistry ; u: Drugs of the Future 29 (2004) (S A) / Prous, J.R. (ur.).
Barcelona: Prous Science, 2004. str. 417-417 (poster, međunarodna recenzija, sažetak, znanstveni)

CROSBI ID: 155420 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Synthesis and Activity of Amidino Substituted 2-Phenylbenzothiazoles

Autori
Racane, Livio ; Kitson, Richard P ; Tralić-Kulenović, Vesna ; Karminski-Zamola, Grace

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Abstracts from the XVIII Internatinal Symposium on Medicinal Chemistry ; u: Drugs of the Future 29 (2004) (S A) / Prous, J.R. - Barcelona : Prous Science, 2004, 417-417

Skup
Internatinal Symposium on Medicinal Chemistry (18 ; 20094)

Mjesto i datum
Kopenhagen, Danska; Malmö, Švedska, 15.08.2004. - 19.08.2004

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
benzothiazole; amidine; antitumor activity

Sažetak
Continuing our studies on the syntheses of some effective compounds against cancer [2, 3] we prepared some new cyano- and amidino-substituted benzothiazoles. Starting with o-aminothiophenole or 2-mercapto-3-amino-benzonitrile and benzaldehyde or p-cyanobenzaldehyde we obtained corresponding mono or dinitriles by condensation reaction. Amidines as hydrochloric salts were prepared by the Pinner reaction of appropiate nitriles. Antitumor evaluation were carried out on 4 human cell lines: DU-145 (prostate carcinoma), HT-1080 (fibrosarcoma), MDA-MB-231 (breast carcinoma) and A549-met (lung adenocarcinoma). All compounds showed certain antiproliferative effect on these cell lines.

Izvorni jezik
Engleski

Znanstvena područja
Kemija



POVEZANOST RADA

Projekti:
0125005

Ustanove:
Tekstilno-tehnološki fakultet, Zagreb,
Fakultet kemijskog inženjerstva i tehnologije, Zagreb

Profili:

Avatar Url Grace Karminski-Zamola (autor)

Avatar Url Vesna Tralić-Kulenović (autor)

Avatar Url Livio Racane (autor)

Citiraj ovu publikaciju:

Racane, Livio; Kitson, Richard P; Tralić-Kulenović, Vesna; Karminski-Zamola, Grace
Synthesis and Activity of Amidino Substituted 2-Phenylbenzothiazoles // Abstracts from the XVIII Internatinal Symposium on Medicinal Chemistry ; u: Drugs of the Future 29 (2004) (S A) / Prous, J.R. (ur.).
Barcelona: Prous Science, 2004. str. 417-417 (poster, međunarodna recenzija, sažetak, znanstveni)
Racane, L., Kitson, R., Tralić-Kulenović, V. & Karminski-Zamola, G. (2004) Synthesis and Activity of Amidino Substituted 2-Phenylbenzothiazoles. U: Prous, J. (ur.)Abstracts from the XVIII Internatinal Symposium on Medicinal Chemistry ; u: Drugs of the Future 29 (2004) (S A).
@article{article, author = {Racane, Livio and Kitson, Richard P and Trali\'{c}-Kulenovi\'{c}, Vesna and Karminski-Zamola, Grace}, editor = {Prous, J.}, year = {2004}, pages = {417-417}, keywords = {benzothiazole, amidine, antitumor activity}, title = {Synthesis and Activity of Amidino Substituted 2-Phenylbenzothiazoles}, keyword = {benzothiazole, amidine, antitumor activity}, publisher = {Prous Science}, publisherplace = {Kopenhagen, Danska; Malm\"{o}, \v{S}vedska} }
@article{article, author = {Racane, Livio and Kitson, Richard P and Trali\'{c}-Kulenovi\'{c}, Vesna and Karminski-Zamola, Grace}, editor = {Prous, J.}, year = {2004}, pages = {417-417}, keywords = {benzothiazole, amidine, antitumor activity}, title = {Synthesis and Activity of Amidino Substituted 2-Phenylbenzothiazoles}, keyword = {benzothiazole, amidine, antitumor activity}, publisher = {Prous Science}, publisherplace = {Kopenhagen, Danska; Malm\"{o}, \v{S}vedska} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus

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