Pregled bibliografske jedinice broj: 155266
The Role of Insulin and IGF-1 Signaling in Longevity
The Role of Insulin and IGF-1 Signaling in Longevity // Cellular and molecular life sciences, 62 (2005), 3; 320-343 (međunarodna recenzija, pregledni rad, znanstveni)
CROSBI ID: 155266 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
The Role of Insulin and IGF-1 Signaling in Longevity
Autori
Katić, Maša ; Kahn, Ronald
Izvornik
Cellular and molecular life sciences (1420-682X) 62
(2005), 3;
320-343
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, pregledni rad, znanstveni
Ključne riječi
aging; lifespan; genetic instability; telomerase; oxidative stress; superoxide dismutase
Sažetak
There are many theories of aging and parameters that influence lifespan, including genetic instability, telomerase activity and oxidative stress. The role of caloric restriction, metabolism and insulin and IGF-1 signaling in the process of aging is especially well conserved throughout evolution. These latter factors interact with each other, the former factors and histone deacetylases of the SIR family in a complex interaction to influence lifespan.
Izvorni jezik
Engleski
Znanstvena područja
Temeljne medicinske znanosti
POVEZANOST RADA
Citiraj ovu publikaciju:
Časopis indeksira:
- Current Contents Connect (CCC)
- Web of Science Core Collection (WoSCC)
- Science Citation Index Expanded (SCI-EXP)
- SCI-EXP, SSCI i/ili A&HCI
- Scopus
- MEDLINE
