Naslov
Glucose-6-phosphate Dehydrogenase Deficiency Among the Population of Komiza on the Island of Vis

Autori
Sapunar, Ada ; Markić, Joško ; Krželj, Vjekoslav ; Bošnjak, Nada

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Clinical Chemistry and Laboratory Medicine (Vol. 42 No. 9) / Siest, Gerard - Berlin : New York : Walter de Gruyter, 2004, A87-A88

Skup
International Swiss MedLab 2004 and 8th Alps Adria Congress

Mjesto i datum
Luzern, Švicarska, 05.10.2004. - 09.10.2004

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Sažetak
The objective of this study was to determine the prevalence of glucose-6-phosphate dehydrogenase (G-6-PD) deficiency among the population of the city of Komiža on the island Vis, part of a region of Middle Dalmatia, which has been reported as a place with several cases of favism. In order to determine it, we performed a population screening using the fluorescent spot test. Fluorescence readings were performed at the beginning and following 5, 10 and 20 min of incubation and were classified into three groups: bright fluorescence, weak fluorescence and no fluorescence. All men found to be deficient by this method were tested with a confirmatory quantitative spectrophotometric method. Of the 302 males tested, 18 (5, 96%) were G-6-PD deficient. It has been found that the prevalence rate of G-6-PD deficiency among men from Komiža is significantly higher (p<0, 001) compared with the prevalence rate in the region of Middle Dalmatia (0, 75% in males, 0, 14% in females). Based on these findings it is recommended that infants originating from the island of Vis should be included into a screening program for G-6-PD deficiency.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA