Pregled bibliografske jedinice broj: 148409
Identification of Plasma Low Density Lipoprotein Subclasses by a New Electrophoresis Method
Identification of Plasma Low Density Lipoprotein Subclasses by a New Electrophoresis Method // Clinical Chemistry and Laboratory Medicine / Siest, Gerard (ur.).
Prag, Češka Republika: Walter de Gruyter, 2001. str. 292-292 (poster, međunarodna recenzija, sažetak, znanstveni)
CROSBI ID: 148409 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Identification of Plasma Low Density Lipoprotein Subclasses by a New Electrophoresis Method
Autori
Trbojević-Čepe, Milica ; Vogrinc, Željka ; Horvat, Dunja ; Stavljenić-Rukavina, Ana
Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni
Izvornik
Clinical Chemistry and Laboratory Medicine
/ Siest, Gerard - : Walter de Gruyter, 2001, 292-292
Skup
14th IFCC-FESCC European Congress of Clinical Chemistry and Laboratory Medicine
Mjesto i datum
Prag, Češka Republika, 26.05.2001. - 31.05.2001
Vrsta sudjelovanja
Poster
Vrsta recenzije
Međunarodna recenzija
Ključne riječi
LDL subclasses; electrophoresis
Sažetak
Human LDL are a heterogenous collection of particles which vary in density, size and lipid and protein composition. Recent investigations have shown that increased proportion of small, dense LDL particles is an important coronary artery disease risk marker. We develop a simple electrophoresis method for separation of LDL particles using a nondenaturating gradient (3, 5-5%) polyacrylamide gel.Using this method, we studied a group of 150 patients with dyslipoproteinemia and 60 controls. Concentrations of total cholesterol, triglycerides, glucose, HDL- and LDL-cholesterol, Lp(a) and apo B were determined in all samples. We established that an increased proportion of small, dense LDL particles has been associated with elevated triglyceride and low HDL-cholesterol concentrations much more frequently than with elevated total and LDL-cholesterol levels.
Izvorni jezik
Engleski