Naslov
Apparent bone mineral density estimated from DXA in healthy men and women

Autori
Cvijetić, Selma ; Koršić, Mirko

Izvornik
Osteoporosis International (0937-941X) 15 (2004); 295-300

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
bone mineral density; bone mineral apparent density; age; anthropometry; risk factors

Sažetak
The aim of this study was to measure bone mineral density (BMD) in healthy people and examine the influence of age, anthropometry and postmenopause on calculated bone mineral apparent density (BMAD). The study included 526 healthy subjects (249 men and 277 women), aged 20 to 79 years. Anthropometric measurements included height, weight and body mass index (BMI). Bone mineral content (BMC) and areal BMD were measured at the lumbar spine and proximal femur, using dual energy X-ray absorptiometry (DXA). The calculation of volumetric density relied on the formula: BMAD=BMD/√ BA (BA=bone area). Association between densitometric parameters and age, height, weight and postmenopause was analyzed with multiple regression. BMC and BMD decreased in older age groups, especially in postmenopausal women. The average annual bone loss in spine was 0.2% in both sexes, whereas femur loss was 0.5% in men and 0.3% in women. Bone area slightly increased in older age groups in both sexes, and BMD loss after the age of 50 could be contributed to bone area increase. To minimize the effect of bone size on bone density, volumetric density and areal density were regressed to age, anthropometry and postmenopause. Age and postmenopause were significantly associated with BMD and BMAD in spine and femur. Furthermore, BMD showed a stronger association with height and weight than BMAD, in both regions. Weaker association of body height and weight with BMAD than with BMD suggests that BMD depends on the bone size and body size and that the different BMD could be the consequence of the difference in that parameters.

Izvorni jezik
Engleski

Znanstvena područja
Javno zdravstvo i zdravstvena zaštita

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