Naslov
Synthesis and anion binding properties of a novel selectively substituted bipyrrole

Autori
Dolušić, Eduard ; Mens, Raoul ; Dehaen, Wim

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Abstracts, 7th Sigma-Aldrich Organic Synthesis Meeting / De Clerq, P. ; Krief, A. ; Marko, I. E. ; Tourwé, Dirk - Spa : Sigma-Aldrich Corporation, 2003, P15-P15

Skup
7th Sigma-Aldrich Organic Synthesis Meeting

Mjesto i datum
Spa, Belgija, 04.12.2003. - 05.12.2003

Vrsta sudjelovanja
Poster

Vrsta recenzije
Nije recenziran

Ključne riječi
bipyrrole; synthesis; Ullmann coupling reaction; 5; 5'-diethoxycarbonyl-3; 3'-di(n-hexyl)-2; 2'-bipyrrole

Sažetak
Bipyrroles are products with a broad spectrum of applications, among them the synthesis of higher cyclic oligopyrroles, including corroles, sapphyrins, porphycenes and new classes of compounds, such as cyclo[8]pyrrole. A number of synthetic procedures have recently been developed to obtain these useful synthons, albeit with varying succcess and usually in a rather low yield. In this work we present an improved synthesis of 5, 5'-diethoxycarbonyl-3, 3'-di(n-hexyl)-2, 2'-bipyrrole, starting with derivatizing pyrrole and finally making the pyrrole-pyrrole link via an Ullmann coupling reaction. All steps have been optimised to give rather high yields and attempts to scale up the synthesis (10+ gram scale) are in progress. Along with the synthesis, the results of binding studies of a number of anions with the bipyrroles, using UV spectrophotometry, are presented in the poster.

Izvorni jezik
Engleski

Znanstvena područja
Kemija, Biologija

POVEZANOST RADA