Naslov
Evaluation of tumour markers in patients with burning mouth syndrome

Autori
Vučićević-Boras, Vanja ; Lukinac, Ljerka ; Cekić-Arambašin, Ana

Izvornik
Oral Oncology (1368-8375) 39 (2003); 742-744

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, pismo, znanstveni

Ključne riječi
tumour markers; burning mouth syndrome

Sažetak
Burning mouth syndrome is an enigmatous condition both for the patient and the clinician, and its diagnosed on the basis of the patients symptoms when they have on examination an apparently healthy looking oral mucosa. A variety of local and systemic factors are known to contribute to burning mouth syndrome. Some authors reported that underlying malignancy could be a possible cause for BMS. In 23 patients with burning mouth syndrome as well as 20 age, sex and race matched healthy controls levels of tumour markers-CEA, CA 19-9, AFP and CYFRA 21-1- were determined from sera. Immunoradiometric assay (IRMA) for detection of ELSA-CEA, ELSA-CA 19-9, ELSA 2-AFP, ELSA-CYFRA 21-1 (CIS bio international, ORIS group, France) was used. Statistical analysis showed no significant differences in the level of tumour markers CEA, CA-19-9, AFP, CYFRA 21-1 in patients with burning mouth syndrome when compared to the healthy controls. We can conclude that evaluation of tumour markers in patients with burning mouth syndrome is not useful and in terms of cost-benefit this investigation should not be performed in patients with burning mouth syndrome.

Izvorni jezik
Engleski

Znanstvena područja
Dentalna medicina

POVEZANOST RADA