Naslov
Anion gap and hypoalbuminemia in critically ill patients

Autori
Pavić, Marina ; Milevoj, Lara ; Hreljac, Melita ; Bronić, Ana

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, stručni

Izvornik
4. hrvatski kongres medicinskih biokemičara : abstracts ; u: Clinical Chemistry and Laboratory Medicine 41 (2003) (S) / - , 2003, S459-S459

Skup
Hrvatski kongres medicinskih biokemičara (4 ; 2003)

Mjesto i datum
Zadar, Hrvatska, 24.09.2003. - 28.09.2003

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
anion gap; hypoalbuminemia; criticaly ill patients

Sažetak
The anion gap(AG) is defined as the difference between the concentration of unmeasured anions und unmeasured cations in the serum. AG was calculated as (Na+K)-(Cl+HCO3). At normal pH all serum proteins are anion and thereby counterbalance a portion of sodiums positive charge. Albumin, the most abundant serum protein, contains a relatively high charge densitiy and consequently has been shown to be responsible for approximately 75% pf the normal AG. The aim was to evaluate to relationship tetween hypoalbumibnnemia and AG. We determined serum electrolyte and albumin concentrations in a group of 58 critically ill patients and 21 healthy volunteers. Samples were analyzed for sodium, potassium, chloride, albumin and HCO3. The anion gap was calculated using the equation above. Our results show that in the group of healthy volunteers mean value of AG was common in critically ill patients and they had significantly lower AG (mean 8 mmol/l) compared to the control group . Our results confirm that, as group ; patients with hypoalbuminemia had lower AG than control subjects although there was no significant correlation between the individual albumin concentrations and decreased AG in the critically ill patients(r=0, 26)

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA