Naslov
Pračenje vrijednosti D dimera u pacijenata sa HIP ozlijedama
(Follow up of D-dimer values in patients with HIP injuries)

Autori
Bronic, A ; Coen, D ; Pavic, M

Izvornik
Clinical chemistry and laboratory medicine. Special supplement (1437-8523) 40 (2002);

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, ostalo

Ključne riječi
D-dimeri; HIP ozlijede; duboke venske tromboze
(D-dimer; HIP injuries; VTE)

Sažetak
D-dimer represents a measure of both clot formation and clot lysis.Their determination represents a non-invasive marker to rule out venous tromboembolism (VTE).The aim of our study was to determine the concentration of D-dimer in elderly patients with hip fractures immediately after injury and subsequently during their hospitalization.D-dimers were measured in 70 patients (11 men, 59 women) aged from 62-95 years in citrated plasma samples by using the mmunofiltration method on the Nycocard Reader II.Obtained values ranged from 0.2 to 19.1 mg/L ( median 4.1) and were above cut off values (0.3 mg/L) in 99% patients.The determination was repeated in plasma samples of 15 patients with initial values 2.0 mg/L on the fourth day after injury before surgey, and in weak after surgery. Decreased levels were observed in all patients before surgey as compared to initial values (0.2-2.7 mg/L).After surgey D-dimer levels monitored to deprease in 2 patients whilst they increasde in 13 patients.According to our results fibrinolys is markely increased immediately after injury.Since a second rise of D-dimer levels were observed after surgey we propose further determinations for excluding postoperative complications (VTE)

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti

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