Naslov
Glycemic control and the risk of preeclampsia in women with gestational diabetes mellitus

Autori
Starčević, Vito ; Đelmiš, Josip ; Ilijić, Marcela ; Tuzović, Lea ; Bljajić, Danko

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Book of Abstracts / XXIV Alpe Adria Meeting, XXVI Congress of Perinatal Medicine / - , 2002

Skup
XXIV Alpe Adria Meeting, XXVI Congress of Perinatal Medicine

Mjesto i datum
Sopron, Mađarska, 25.10.2002. - 28.10.2002

Vrsta sudjelovanja
Predavanje

Vrsta recenzije
Nije recenziran

Ključne riječi
gestacijski dijabetes; preeklampsija
(gestational diabetes; preeclampsia)

Sažetak
Background: Gestational diabetes mellitus is associated with an increased risk of preeclampsia. Subject and methods: During the period 1992-2001, we followed up 472 consecutive unselected pregnancies in women with gestational diabetes mellitus. Glycemic control was assessed by HbA1c at the time of diagnose. Preeclampsia was defined as RR>140/90 mmHg combined with albuminuria of >0.3 g/L. The occurrence of preeclampsia was also associated in a control group comprising 324 unselected pregnant women. Results: Preeclampsia developed in 14, 4% of the women with gestational diabetes and in 4.3% of the controls. After adjustment by logistic regression, both the FBG and PBG and their changes during pregnancy remained significant predictors for preeclampsia. The odds for preeclampsia increased by a factor of 1.2 for each 1mmol/L increment in the initial FBG level and PBG level, and decreased by a factor of 0.8 for each 1mmol/L decreased of FBG or PBG level achieved during pregnancy. Conclusion: An improvement of the glycemic control during pregnancy reduces risk of preeclampsia.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA