Naslov
Symptoms prevalence in patients with gastrointestinal cancers : before versus after chemotherapy

Autori
Dobrila-Dintinjana, Renata ; Milić, Sandra ; Ružić, Alen ; Štimac, Davor

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, stručni

Izvornik
Abstracts of the 10th United European Gastroenterology Week (UEGW) ; u: Gut 43 (2002) (S) ; Poster Presentaion / - , 2002, 51-51

Skup
United European Gastroenterology Week (10 ; 2002)

Mjesto i datum
Padova, Italija, 2002

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
gastrointestinal cancers; symptoms; chemotherapy

Sažetak
Patients (pts) with gastrointestinal cancers suffer from many symptoms during their disease (1-25). Pain is the most prevalent symptom in cancer pts.Its occur in 70-90% of pts with advanced disease. Fatigue is the most frequently reported symptom in cancer patients undergoing chemotherapy (cht). The aim of this study was to compare the symptoms prevalence and its severity in cht naive pts versus after cht protocols were applied. 132 pts were inrolled into the study, there were 48 female and 74 male, with mean age of 64, 2 years.There were 86 (65, 1%) pts with metastatic or locally advanced disease. The most common cancer site was colorectal and pancreatic cancer. In follow-up period 264 cycles were applicated. Symptoms severity levels (mild, moderate, severe) had been evaluated in all pts at the start, after 1st and 2nd cycle of CPF (cisplatin, 5-fluorouracil and leucovorin) cht protocol. The most common symptoms reported in cht naive pts were pain in multiple sites (69, 7%), anorexia (53%), sleeping disorders (53%) and fatigue (47%). After 1st cycle of CPF cht, anorexia 56, 1%, fatigue 54, 5%, sleeping disorders 31, 8% and pain in 22, 7% pts were the most common symptoms. Fatigue 85, 6%, depression 58, 3%, anorexia 51, 5% and pain 17, 4% were the most reported symptoms after 2nd cycle of cht. With adequate analgetic therapy, pain become good controlled symptom, but fatigue experience during cht is a serious problem. Although CPF is middle toxic cht protocol, significant number of pts developed severe fatigue supporting the need for better fatigue management.

Izvorni jezik
Engleski

Znanstvena područja
Javno zdravstvo i zdravstvena zaštita

Napomena
Rad je kao poster prezentiran na istom skupu održanom od 19.-23.10.2002., Ženeva, Švicarska.

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