Pregled bibliografske jedinice broj: 1319
Regional differences in NaCl-induced increase of the potency of bicuculline to displace (3H)/muscimol binding
Regional differences in NaCl-induced increase of the potency of bicuculline to displace (3H)/muscimol binding // Neurochemistry international, 30 (1997), 2; 199-202 doi:10.1016/S0197-0186(96)00054-X (međunarodna recenzija, članak, znanstveni)
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Naslov
Regional differences in NaCl-induced increase of the potency of bicuculline to displace (3H)/muscimol binding
Autori
Bujas, Maja ; Tvrdeić, Ante ; Peričić, Danka
Izvornik
Neurochemistry international (0197-0186) 30
(1997), 2;
199-202
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni
Ključne riječi
(3H)muscimol binding; regional differences; bicuculline; NaCl
Sažetak
It has been shown that the potency of bicuculline to displace [H-3]muscimol binding to crude brain membranes can be enhanced markedly by different anions. This study shows that although bicuculline alone was a more potent displacer of [H-3]muscimol binding in cortical than in cerebellar membranes, the NaCl (250 mM)-induced leftward shift of the bicuculline inhibition curve of [H-3]muscimol binding was considerably higher in cerebellum than in cortex. The same concentration of NaCl failed to affect either the affinity or the density of cortical and cerebellar [H-3]muscimol binding sites. The results suggest that sodium chloride is able to reveal regional differences in bicuculline potency.
Izvorni jezik
Engleski
Znanstvena područja
Temeljne medicinske znanosti
Citiraj ovu publikaciju:
Časopis indeksira:
- Current Contents Connect (CCC)
- Web of Science Core Collection (WoSCC)
- Science Citation Index Expanded (SCI-EXP)
- SCI-EXP, SSCI i/ili A&HCI
- Scopus
- MEDLINE
