Naslov
Coagulation changes in patients with severe preeclampsia and fetal growth

Autori
Kendić, Sulejman ; Đelmiš, Josip ; Starčević, Vito ; Ivanišević, Marina

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, stručni

Izvornik
Abstracts of the XVI. European Congress of Perinatal Medicine, Prenatal and Neonatal Medicine : International Journal of Basic and Clinical Research and Practice, 3 (1998), suppl. 1 / Di Renzo, Gian Carlo - Huddersfield : The Parthenon Publishing Group, 1998, 117-117

Skup
XVI. European Congress of Perinatal Medicine

Mjesto i datum
Zagreb, Hrvatska, 10.06.1998. - 13.06.1998

Vrsta sudjelovanja
Poster

Vrsta recenzije
Nije recenziran

Ključne riječi
eclampsia; fetal growth; blood coagulation

Sažetak
Objective: Coagulation changes often occur in pregnancies complicated with preeclampsia. The aim of the study was to evaluate coagulation changes and foetal growth. Study design: In this study 31 pregnant with severe preeclampsia and 39 healthy pregnant women were analysed, during their pregnancy, delivery and foetal growth. Results: An evident change in coagulation factors and fibrinolysis occurred in preeclamptic women in comparison to healthy pregnant women. In order to analyse influence of coagulation changes and foetal growth we have made linear regression analysis. Correlation has been found between foetal growth and fibrinolysis (r=0.3; p<0.004). With fibrinolysis slowing down a higher birthweight occurred. In this study a statistically significant correlation was found between FDP and neonatal birthweight (r=-0.3; p<0.008). Birthweight showed correlation with coagulation factor VIII (r=0.21; p<0.03). Conclusions: Elevation of FDP, decrease in coagulation factor VIII and activation of fibrinolysis in studied group when compared to the control group are the result of intravascular fibrin deposition which leads to foetal intrauterine growth retardation.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA