Pregled bibliografske jedinice broj: 1282919
The Genomics-Driven Discovery of Novel Surface Polysaccharide Modification Pathways in Bacteria: Prospects for Future Antimicrobial Drug Discovery
The Genomics-Driven Discovery of Novel Surface Polysaccharide Modification Pathways in Bacteria: Prospects for Future Antimicrobial Drug Discovery // Clinical Microbiology: Open Access, 10 (2021), 10; 1000230, 2 (međunarodna recenzija, komentar, ostalo)
CROSBI ID: 1282919 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
The Genomics-Driven Discovery of Novel Surface Polysaccharide Modification Pathways in Bacteria: Prospects for Future Antimicrobial Drug Discovery
Autori
Simunović, Vesna
Izvornik
Clinical Microbiology: Open Access (2327-5073) 10
(2021), 10;
1000230, 2
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, komentar, ostalo
Ključne riječi
polysaccharide modification ; bacteria ; drug discovery
Sažetak
Bacterial surface-associated polysaccharides represent the first line of defense towards the outside environment. Hence, the ability of bacteria to quickly respond and adapt to external conditions directly impacts their overall fitness and survival. Throughout evolution, bacteria have evolved multiple mechanisms that help them survive in the often harsh and extreme conditions of their host immune systems or other natural habitats. Among them, alteration of the cell surface associated components such as polysaccharides and/or lipids and transition to a metabolically dormant, biofilm-forming lifestyle are some of the most widely employed adaptation strategies.
Znanstvena područja
Interdisciplinarne prirodne znanosti, Farmacija
