Naslov
Enzymatic modifications of sophorolipids: From biorefineries to valorization

Autori
Mateša, Lorena ; Sudar, Martina ; Domínguez de María, Pablo ; Findrik Blažević, Zvjezdana

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, stručni

Izvornik
Book of abstracts - BIOTRANS - International Symposium on Biocatalysis & Biotransformations / - La Rochelle, 2023, 762-763

Skup
Biotrans 2023 16th International Symposium on Biocatalysis & Biotransformations

Mjesto i datum
La Rochelle, Francuska, 25.06.2023. - 29.06.2023

Vrsta sudjelovanja
Poster

Vrsta recenzije
Recenziran

Ključne riječi
sophorolipids, biorefineries, reaction optimization, mathematical modeling

Sažetak
Sophorolipids (SLs) are a broadly known family of biosurfactants, composed of a sophorose head glycosidicaly bonded to the carbon of the long hydroxyl fatty acid [1]. Sophorolipids are typically produced by non-pathogenic yeasts, with main microorganism used for cultivation being Candida bombicola. Sophorolipids obtained in this manner are a mixture of structurally related molecules [2]. Different structures of sophorolipid molecules result in differences in their biological and physicochemical properties and, consequently, in several fields of application [3]. Sophorolipid molecules obtained by fermentation have industrial applications on their own, but some structural variations are desirable to further broaden their scope [4]. Enzymatic modifications offer the possibility to synthesize new derivatives by inserting other functional groups, which cannot be obtained via the fermentation process. Exposure of sophorolipids to enzymes could provide means towards the defined modification of sophorolipids [5]. Many examples are given on alteration of the fatty acid carboxylic end and the sophorose acetylation pattern, although examples of modifications of the sugar part of the sophorolipid are limited [6]. In this work, the main promising working lines for sophorolipid valorization are described, to establish a rational strategy to afford novel sophorolipid compounds with different applications and properties. Moreover, strategies for the synthetic improvement of sophorolipid derivatives, e.g., biorefinery-like cascading, use of biobased solvents, and reaction optimization using mathematical modelling, will be discussed.

Izvorni jezik
Engleski

Znanstvena područja
Kemijsko inženjerstvo, Biotehnologija

POVEZANOST RADA