Pregled bibliografske jedinice broj: 1282059
Serological Response to SARS-CoV-2 Vaccine in Hemodialyzed Patients and the Association with Later COVID-19 Positivity
Serological Response to SARS-CoV-2 Vaccine in Hemodialyzed Patients and the Association with Later COVID-19 Positivity // Antibodies, 12 (2023), 2; 37-37 doi:10.3390/antib12020037 (međunarodna recenzija, članak, znanstveni)
CROSBI ID: 1282059 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Serological Response to SARS-CoV-2 Vaccine in
Hemodialyzed Patients and the Association with
Later COVID-19 Positivity
Autori
Premužić, Vedran ; Stevanović, Ranko ; Vilibić- Čavlek, Tatjana ; Sirovica, Maja ; Stalman, Sara ; Bogdanić, Maja ; Žilić, Denis ; Nakić, Dario ; Santini Dušević, Danijela ; Vojković, Marina ; Barbić, Jerko ; Durlen, Ivan ; Grdan, Željka ; Pavlović, Draško ; Kudumija, Boris ; Sefer, Siniša ; Griparić, Davor ; Rogić, Dunja ; Bubaš, Marija ; Capak, Krunoslav ; Jelaković, Bojan
Izvornik
Antibodies (2073-4468) 12
(2023), 2;
37-37
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni
Ključne riječi
serological response ; SARS-CoV-2 ; hemodialysis ; vaccination ; COVID-19
Sažetak
Background: The effectiveness of the COVID-19 vaccine may differ in hemodialysis patients. The aim of this prospective multicenter study was to determine the degree of serological response to the SARS-CoV-2 vaccine in the population of dialysis patients and its association with later SARS-CoV-2 infections. Methods: A blood sample was taken for the determination of COVID-19 serological status (IgG antibodies) in 706 dialysis patients 16 weeks after vaccination with the second dose (Pfizer-BioNTech). Results: Only 314 (44.5%) hemodialyzed patients had a satisfactory response to the COVID-19 vaccine. Eighty-two patients (11.6%) had a borderline response, while 310 patients (43.9%) had an unsatisfactory (negative) post-vaccinal antibody titer. A longer dialysis vintage had an increased odds ratio (OR) of 1.01 for the occurrence of COVID-19 positivity after vaccination. In the group of subsequently positive patients, 28 patients (13.6%) died from complications of COVID- 19. We have found differences in mean survival time between patients with and without appropriate responses to vaccination in favor of patients with a satisfactory serological response. Conclusions: The results showed that the dialysis population will not have the same serological response to the vaccine as the general population. The majority of dialysis patients did not develop a severe clinical picture or die at the time of positivity for COVID-19.
Izvorni jezik
Engleski
Znanstvena područja
Kliničke medicinske znanosti, Javno zdravstvo i zdravstvena zaštita
POVEZANOST RADA
Ustanove:
Hrvatski zavod za javno zdravstvo,
Medicinski fakultet, Zagreb,
Klinički bolnički centar Osijek,
Klinička bolnica "Sveti Duh",
KBC "Sestre Milosrdnice",
Opća bolnica Varaždin,
Klinička bolnica "Dubrava",
Klinički bolnički centar Zagreb,
Opća bolnica Zadar
Profili:
Dunja Rogić (autor)
Dario Nakić (autor)
Maja Bogdanić (autor)
Draško Pavlović (autor)
Jerko Barbić (autor)
Ranko Stevanović (autor)
Bojan Jelaković (autor)
Krunoslav Capak (autor)
Marija Bubaš (autor)
Danijela Santini Dušević (autor)
Tatjana Vilibić-Čavlek (autor)
Vedran Premužić (autor)
Citiraj ovu publikaciju:
Časopis indeksira:
- Web of Science Core Collection (WoSCC)
- Emerging Sources Citation Index (ESCI)
- Scopus