Naslov
Simoltaneus determination and quantification of five biflavones in ginkgo (Ginkgo biloba L.) leaves

Autori
Šamec, Dunja ; Kovač Tomas, Marija ; Jurčević, Iva

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
5th International Conference on Natural Products Utilization- From Plants to Pharmacy Shelf- Book of Abstracts / Georgiev, Milen I. - , 2023, 236-236

ISBN
978-954-25-0390-3

Skup
5th International Conference on Natural Products Utilization- From Plants to Pharmacy Shelf (5-ICNPU)

Mjesto i datum
Varna, Bugarska, 30.05.2023. - 02.06.2023

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
biflavones, HPLC, Ginkgo biloba L.

Sažetak
Biflavonoids are flavonoid dimers that are much less studied than monomeric flavonoids. Plant species in which various biflavonoids have been reported is ginkgo (Ginkgo biloba L.), whose leaves are used worldwide to treat cognitive complaints. Flavonoids are considered compounds that contribute significantly to the health benefits of ginkgo leaves, but most studies focus on monomeric flavonoids and biflavonoids are often neglected. To fill this gap in our knowledge of ginkgo flavonoids, the aim of the present study was to profile biflavonoids in ginkgo leaves. To this end, we developed HPLC-DAD method, which allowed us to determine five biflavonoids simultaneously: amentoflavone, bilobetin, ginkgetin, isoginkgetin, and sciadopitysin, and we quantified their content in the petioles and leaf blade of ginkgo. In petioles, the most abundant biflavonoid was bilobetin (984.48 ± 6.42 µg/g dw), followed by isoginkgetin, sciadopitysin, and ginkgetin. In leaf blades, the most abundant biflavonoid was sciadopitysin (2398.59 ± 6.11 µg/g dw), followed by isoginkgetin and bilobetin and ginkgetin, whose contents were similar. In the leaves, we found amentoflavone at a much lower concentration, indicating the dominance of the methylated form of biflavones, which have been associated with potential for treating various inflammation-related diseases such as cancer, cardiovascular disease, inflammation caused by viruses and bacteria, and neurodegenerative disorders. Acknowledgements: This work was funded by the Croatian Science Foundation under the project “Biflavonoids role in plants: Ginkgo biloba L. as a model system” (UIP-2019-04-1018).

Izvorni jezik
Engleski

Znanstvena područja
Biologija, Biotehnologija, Prehrambena tehnologija

POVEZANOST RADA