Naslov
Comparative study of cyclodextrin binding affinities for diamondoid alcohols

Autori
Požar, Josip ; Usenik, Andrea ; Alešković, Marija ; Roca, Sunčica ; Mrkuš, Iva ; Šekutor, Marina

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
7th Adriatic NMR Conference : Book of Abstracts / Bregović, Nikola ; Namjesnik, Danijel ; Novak, Predrag ; Parlov Vuković, Jelena - Croatian Chemical Society Zagreb, 2023, 49-49

Skup
7th Adriatic NMR Conference

Mjesto i datum
Mali Ston, Hrvatska, 01.06.2023. - 04.06.2023

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
Cyclodextrins (β-CD and γ-CD) ; ITC and NMR spectroscopy ; adamantane and diamantane alcohols

Sažetak
The temperature and solvent effect on the complexation of adamantane and diamantane alcohols by cyclodextrins (β-CD and γ-CD) in water, formamide, and ethylene glycol was investigated by means of ITC and NMR spectroscopy. The predominantly exothermic binding of all guests by β-CD in water was observed at 298 K, whereas the inclusion within γ-CD was entirely entropy-driven, with the exception of diamantan-1-ol. β-CD was a better receptor for explored guests, especially for adamantan-1-ol and apical diamantane alcohols. In the case of both receptors, the complex stability increased with the size of included hydrophobic surface. A pronounced decrease of ΔrH° and ΔrS° with temperature, resulting in weak ΔrG° (T) dependence, was observed for all studied systems. The effect is predominantly due to the disordering of the guest-hydrating water, which gradually shifts from classical to non-classical as the temperature increases. Unlike in water, the binding of alcohols with β-CD in organic solvents was exothermic and accompanied with negative entropy changes over the explored temperature range.

Izvorni jezik
Engleski

Znanstvena područja
Kemija

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