Naslov
Changes in nutritional status in patients on peripheral stem cell transplantation

Autori
Pomper, Ljiljana ; Vidović, Irena ; Jakovac, Ruža

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, stručni

Izvornik
Bone Marrow Transplantation / - Frankfurt : Annual Meeting of the European Society for Blood and Marrow Transplantation: Nurses Group, 2019, 659-660

Skup
45st Annual Meeting of the European Group for Blood and Marrow Tranplantation and 35st Meeting of the EBMT Nurses Group

Mjesto i datum
Online ; Frankfurt na Odri, Njemačka, 24.03.2019. - 27.03.2019

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
malnutrition, hematologic patients, quality of life

Sažetak
Background: PBSCT is a procedure that increases the risk of malnutrition of hematologic patients, which may be associated with multiple complications and poorer quality of life for patients during and after the procedure. Identification of patients with nutritional risk and monitoring of nutritional status changes allows timely interventions to prevent further deterioration and improve outcomes. Methods: From 1 April to 30 September 2018, a prospective study was performed on 39 consecutive patients treated by PBSCT procedure, who were in protective isolation rooms. There were 21 men and 18 women. Median age was 62 (22-68), 26 patients were with Multiple Myeloma, 11 NHL patients, and 2 patients with Hodgkin´s lymphoma. The conditioning protocols were high doses of melphalan (26 patients with myeloma) and BEAM (13 patients with NHL). Nutritional status was assessed using the Risk Assessment Form NRS 2002 at the beginning of hospitalization, discharge and post-release examinations, and for subtle physical changes the Tanita MC-780 scale was used. Results: The median of hospitalization duration was 18 days. Most of the patients (92.3%) had NRS 2002 3 points at start. According to BMI 13 (33.3%) it was normal, 17 (43.6%) had excessive body weight, 7 (17.9%) was obese, 1 (2.56%) was extremely obese and only one patient (2.56%) was malnourished. At the end of hospitalization, BMI was underweight for 2 patients (5.12%). Only 3 patients (7.69%) at the beginning of hospitalization had less energy intake than needed. Only 4 patients (10.29%) lost their body weight back 3 months. During hospitalization, 37 patients (94.87%) lost body weight, while 2 patients (5.12%) increased body weight of less then 1%. Body weight loss was significant (≥5% body weight) in 16 patients (41, 02%), of which only 1 patient lost> 10%. According to NRS 2002, 18 patients were undernourished during at the end of hospitalization (BMI < 20.5%, food intake < 60%, weight loss> 5%). Food interventions were performed in all patients, while the enteral composition was taken by only 3 patients at the time of admission, 2 during hospitalization and 2 at discharge, and parenteral diet during hospitalization by 1 patient. The changes in evaluated parameters are shown in Table 1, showing base-line and end evaluation, quantification of changes and statistical significance in paired t-test. In addition, those parameters although consistently well correlate among themselves also cover different aspects of nutritional impairment and thus enable more complete evaluation of complex clinical problem. Conclusions: The nutrition status can be more precisely evaluated than is usually done. The results obtained by the presented evaluation panel are discrete, but statistically significant and consistent. This supports the wider application of the analyzed parameters panel in routine clinical practice. The process of evaluating the nutritional status can provide credible and unbiased estimates of discrete nutritional status and provide the basis for a rational approach to their correction. Disclosure: No conflict of interest.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti, Javno zdravstvo i zdravstvena zaštita

POVEZANOST RADA