Naslov
In vitro antimicrobial susceptibility of ureaplasma urealyticum
(In vitro antimicrobial susceptibility of ureaplasma urealyticum)

Autori
Petković, Dobrinka ; Vuković, Borislav ; Cviljević, Sabina ; Musil, Ankica

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Knjiga Sažetaka / - , 2017, 60-60

Skup
9. hrvatski kongres o urogenitalnim i spolno prenosivim infekcijama s međunarodnim sudjelovanjem

Mjesto i datum
Opatija, Hrvatska, 12.05.2017. - 14.05.2017

Vrsta sudjelovanja
Poster

Vrsta recenzije
Domaća recenzija

Ključne riječi
ureaplasma urealyticum

Sažetak
Introduction: Ureaplasma urealyticum is commensal of the lower genitourinary tract and causes sexually transmitted diseases. Antimicrobial resistance to tetracyclines and macrolides is low, and to quinolones high. Objective: To determine the prevalence and in vitro antimicrobial susceptibility of U. urealyticum in urogenital samples of women of reproductive age. Materials and methods: In 2005 / 2006. was evaluated in vitro antimicrobial susceptibility of U. urealyticum from urogenital samples 72 patients with urethral syndrome and the results were compared with 181 positive isolates on U. Urealyticum from the genitourinary tract of patients with gynecological issues in 2015. For identification of U. urealyticum we used Mycoplasma IST 2 kit. In vitro antimicrobial susceptibility of the isolates high concentrations ≥ 104 CCU / ml was determined by dilution method in broth to 7 antibiotics: doxycycline, tetracycline, azithromycin, erythromycin, clarythromycin, ciprofloxacin, ofloxacin. Results: In 2005/2006. the prevalence of U. urealyticum in women of reproductive age was 28% and 22, 7% in 2015.The results in vitro antimicrobial susceptibility for the period 2005- 2015. were the following: sensitivity to doxycycline 100% -97, 8%, tetracycline 100%-97, 8%, clarithromycin 93.7% -89.5%, erythromycin 90.3% -85.6%, azithromycin 87%-81, 2%, ofloxacin 62- 59.7%, ciprofloxacin 40.3% -28.9%. Registered the low rate of resistance to doxycycline and tetracyclines (2.2%) and the macrolides (clarithromycin 6.3% -10.5% ; erythromycin 9.7% -14.4% ; azithromycin 13% -18.8%) and high to quinolones (ofloxacin 38% -40.3% ; ciprofloxacin 59% -71.1%). Conclusion: Despite the high sensitivity of U. urealyticum to tetracyclines and macrolides as a first-line treatment, due to the increasing trend of resistance is necessary to continuously monitor in vitro antimicrobial susceptibility in the local region for the purpose of an adequate choice of antibiotics.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

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