Naslov
Do patients from routine practice refl ect clinical study population? First line treatment of metastatic HER2 positive breast cancer in University Clinical Centre Zagreb

Autori
Radmilović Varga, Ljubica ; Križić, Marija ; Kulić, Ana ; Podolski, Paula ; Bašić Koretić, Martina ; Herceg, Davorin ; Vrbanec, Damir ; Dedić Plavetić, Natalija

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, stručni

Izvornik
Libri oncologici / - , 2017, 33-33

Skup
9. godišnji sastanak Hrvatskog društva za internističku onkologiju Hrvatskog liječničkog zbora s međunarodnim sudjelovanjem 11. radni sastanak Sekcije za onkološku farmaciju Hrvatskog farmaceutskog društva s međunarodnim sudjelovanjem

Mjesto i datum
Varaždin, Hrvatska, 20.10.2017. - 21.10.2017

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
clinical study, metastatic breast cancer

Sažetak
Thanks to the Cleopatra study, the dual HER2 blockade together with chemotherapy has become the standard of first line treatment for HER2-positive metastatic breast cancer. We analyzed and compared clinicopathological characteristics (age, metastases sites and hormone receptor status) between a cohort of women included in Cleopatra study and our cohort of women with HER2-positive metastatic breast cancer treated with trastuzumab, pertuzumab and chemotherapy.When we compare clinicopathological characteristics of these two cohorts we can conclude that our cohort had more patients older than 65 and also older than 75 years. Furthermore, our cohort has more women with hormone receptor positive breast cancers in comparison to the Cleopatra study cohort. We will continue collecting and tracking patients because these are too small numbers to definitely conclude that the patients from everyday practice have different clinical and pathological characteristics compared to the study population.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA