Naslov
Adjuvant therapy for breast cancer today

Autori
Silovski, Tajana

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, stručni

Izvornik
Libri oncologici / - , 2020, 7-8

Skup
13. Hrvatski onkološki kongres

Mjesto i datum
Opatija, Hrvatska, 03.09.2020. - 06.09.2020

Vrsta sudjelovanja
Predavanje

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
breast cancer, adjuvant therapy

Sažetak
Adjuvant systemic therapy is delivered after surgical treatment. It depends on individual risk of relapse and predicted sensitivity to treatment as well as benefit and toxicity of the therapy, comorbidity and collaboration between the health care team and patient. The strongest prognostic factors in early breast cancer are expression of estrogene and progesterone receptor (ER/PR), HER2 and proliferation index, number of involved regional lymph nodes, tumor histology, size, grade and presence of peritumoral vascular invasion.Those parameters integrated into different scoring systems allow relatively accurate estimation of the probability of recurrence and death from breast cancer. Accordingly, clinicians can objectively estimate outcome with local treatment only and benefit expected from systemic adjuvant therapy.The final decision on adjuvant therapy should incorporate predictive treatment sequelae, patient’s biological age, general health status, comorbidities and preferences.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA