Naslov
SMOKING IN SCHIZOPHRENIA: AN UPDATED REVIEW

Autori
Šagud, Marina ; Vuksan-Ćusa, Bjanka ; Jakšić, Nenad ; Mihaljević-Peleš, Alma ; Rojnić Kuzman, Martina ; Pivac, Nela

Izvornik
Psychiatria Danubina (0353-5053) 30 (2018), Suppl. 4; 216-223

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
cigarette smoking ; nicotine dependence ; schizophrenia ; negative symptoms ; cognitive dysfunction ; antipsychotic concentration

Sažetak
Patients with schizophrenia continue to have the highest rate of both smoking and heavy nicotine dependence. The interaction between smoking and schizophrenia is complex. There is evidence of the shared genetic background. Recent preclinical and clinical research has further investigated self- medication hypothesis, given that nicotine might alleviate cortical dysfunction. While prior research indicated some favorable effects of smoking on cognitive performance, particulatly on attention/vigilance, recent studies did not confirm those findings. Lower severity of negative symptoms in smokers was not confirmed across studies. Cigarette smoking decreases clozapine and olanzapine concentrations. There is no consistent evidence of favorable effects of nicotine on symptoms in schizophrenia, but the evidence of detrimental effects of smoking on general health is highly consistent. Smoking cessation should be a priority in patients with schizophrenia.

Izvorni jezik
Engleski

POVEZANOST RADA