Pregled bibliografske jedinice broj: 1274100
Development of analytical method for in vitro release testing of dexamethasone nanosuspensions
Development of analytical method for in vitro release testing of dexamethasone nanosuspensions // Dissolution Technologies, 26 (2019), 2; 40-46 doi:10.14227/dt260219p40 (međunarodna recenzija, članak, znanstveni)
CROSBI ID: 1274100 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Development of analytical method for in vitro
release testing of dexamethasone nanosuspensions
Autori
Šutić, Antonia ; Romić, Marieta Duvnjak ; Miočić, Sandra ; Cetina-Čižmek, Biserka
Izvornik
Dissolution Technologies (1521-298X) 26
(2019), 2;
40-46
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni
Ključne riječi
dexamethasone ; nanosuspension ; in vitro release testing (IVRT) ; immersion cell ; vertical diffusion cell ; dialysis bag membrane method
Sažetak
The aim of this study was to develop and compare analytical methods for in vitro release testing (IVRT) of an active substance, dexamethasone, from nanosuspension using three apparatuses for IVRT of topical formulations (immersion cell, vertical diffusion cell, and dialysis bag membrane methods), taking into account the physiological conditions at the point of application of these therapeutic systems. Sensitive and reproducible methods to assess in vitro release rates were developed, and immersion cell method was chosen as most appropriate for evaluation of dexamethasone release.
Izvorni jezik
Engleski
Znanstvena područja
Farmacija
POVEZANOST RADA
Ustanove:
Farmaceutsko-biokemijski fakultet, Zagreb,
PLIVA HRVATSKA d.o.o.
Citiraj ovu publikaciju:
Časopis indeksira:
- Web of Science Core Collection (WoSCC)
- Science Citation Index Expanded (SCI-EXP)
- SCI-EXP, SSCI i/ili A&HCI
- Scopus
