Pregled bibliografske jedinice broj: 1271038
Chiral phosphoric acid-catalyzed Friedel–Crafts reaction of 2,5-disubstituted and 2- monosubstituted pyrroles with isoindolinone- derived ketimines
Chiral phosphoric acid-catalyzed Friedel–Crafts reaction of 2,5-disubstituted and 2- monosubstituted pyrroles with isoindolinone- derived ketimines // Organic & biomolecular chemistry, 21 (2023), 16; 3381-3387 doi:10.1039/d3ob00326d (međunarodna recenzija, članak, znanstveni)
CROSBI ID: 1271038 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Chiral phosphoric acid-catalyzed Friedel–Crafts
reaction of 2,5-disubstituted and 2-
monosubstituted pyrroles with isoindolinone-
derived ketimines
Autori
Beriša, Arben ; Gredičak, Matija
Izvornik
Organic & biomolecular chemistry (1477-0520) 21
(2023), 16;
3381-3387
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni
Ključne riječi
Friedel–Crafts reaction
Sažetak
The enantioselective reaction between 2, 5- disubstituted pyrroles and diaryl-ketimines, generated in situ from isoindolinone-derived alcohols, is described. Pyrrole derivatives possessing a congested tetrasubstituted stereogenic center at the β-(C3) position are generally obtained in high yields and enantioselectivities. The transformation can be extended to 2-monosubstituted pyrroles, generating chiral α-(C5) functionalized pyrrole products. Control experiments were conducted in order to elucidate the origin of the low enantioselectivities observed in some of the products.
Izvorni jezik
Engleski
Znanstvena područja
Kemija
POVEZANOST RADA
Projekti:
HRZZ-IP-2018-01-4053 - Nove strategije za pripravu tetrasupstituiranih kiralnih centara: asimetrične katalitičke reakcije usmjerene protuanionom (NSYNC-ACDC) (Gredičak, Matija, HRZZ - 2018-01) ( CroRIS)
Ustanove:
Institut "Ruđer Bošković", Zagreb
Citiraj ovu publikaciju:
Časopis indeksira:
- Current Contents Connect (CCC)
- Web of Science Core Collection (WoSCC)
- Science Citation Index Expanded (SCI-EXP)
- SCI-EXP, SSCI i/ili A&HCI
- Scopus
- MEDLINE
