Naslov
Process intensification through miniaturization

Autori
Šalić, Anita

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Book of Abstracts 28th Croatian Meeting of Chemists and Chemical Engineers / Rogošić, Marko - Zagreb : Hrvatsko društvo kemijskih inženjera i tehnologa (HDKI), 2023, 22-22

Skup
28th Croatian Meeting of Chemists and Chemical Engineers

Mjesto i datum
Rovinj, Hrvatska, 28.03.2023. - 31.03.2023

Vrsta sudjelovanja
Pozvano predavanje

Vrsta recenzije
Domaća recenzija

Ključne riječi
intenzification, microreactor, biocatalysis

Sažetak
Redesigning equipment or combining multiple processes in a continuous production line can result in significant increases in process throughput. Scaling down of processes to increase mass and heat transfer (Fig. 1A), increase surface-to-volume ratios, and shortened diffusion paths can significantly affect the outcome of various chemical and biochemical processes. The introduction of microfluidics is one of the most promising redesigns of equipment in the field of chemical engineering. The shift to flow technology and micro-scale brought many additional positive benefits, such as better process control and higher productivities. Reactions are often accelerated and the processes that take hours or days in batch reactor can be carried out in microreactors in a few seconds/minutes. The reduction of reaction time also minimizes the formation of various by-products and increases the overall productivity of the process (Fig 1B). Modularity is one of the advantages of microfluidic systems, too, which allows for the integration of several different steps in a small space (even in one micro-system). With this approach, it is possible to combine several reaction steps with parallel purification in one continuous process stream. The use of microfluidics further simplifies the scale-up of the process, since the scale-up is based only on increasing the number of reactors (numbering-up) and not on increasing the scale itself. Microfluidics thus retain all their properties, and once the process has been optimized in a single unit, the optimal conditions are transferred to each additional unit, which can be connected either in parallel or in series. In this presentation several case studies will be presented where microfluidics have been used to intensify various processes such as extraction (extraction of proteins and polyphenols), biocatalysis (hexanal production and coenzyme regeneration, biodiesel synthesis), organic (photo)synthesis, and click reactions.

Izvorni jezik
Engleski

Znanstvena područja
Kemijsko inženjerstvo

POVEZANOST RADA