Naslov
Like-charge pairing of guanidinium cations in water: FTIR and quantum chemical study

Autori
Vojta, Danijela ; Horvat, Tomislav ; Mohaček-Grošev Vlasta ; Vazdar, Mario

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Book of Abstracts / - Jena, 2017

Skup
European Conference on Nonlinear Optical Spectroscopy

Mjesto i datum
Jena, Njemačka, 02.04.2017. - 05.04.2017

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
Guanidinium ; Ammonium ; Like-charge pairing ; FTIR spectroscopy ; Quantum-chemical calculations

Sažetak
Like-charge pairing of guanidinium (Gdm+) cations in side chains of arginine amino acids is responsible for numerous biologically important interactions, such as aggregation of poly- arginines at biological membranes. [1] Although the favorable Gdm+···Gdm+ interaction have been already reported in calculation studies [2], a solid experimental evidence for this interaction is still missing. In this study, we performed a Fourier transformed infrared spectroscopic (FTIR) study supported with calculation results and we demonstrate that certain FTIR spectral changes are attributed to like-charge pairing of Gdm+ cations in aqueous solutions (Figure 1, left). In contrast, we show that this effect does not exist in ammonium chloride solutions in same experimental conditions (Figure 1, right), thus confirming a counterintuitive Coulomb-defying interaction between positively charged Gdm+ ions in water.

Izvorni jezik
Engleski

Znanstvena područja
Kemija

POVEZANOST RADA