Pregled bibliografske jedinice broj: 1262884
Molecular diversity of BLLF1 gene in EBV positive pediatric patients with infectious mononucleosis
Molecular diversity of BLLF1 gene in EBV positive pediatric patients with infectious mononucleosis // HIV Sibiu Dialogues V
Bukurešt, Rumunjska, 2022. str. 1-2 (predavanje, međunarodna recenzija, sažetak, znanstveni)
CROSBI ID: 1262884 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Molecular diversity of BLLF1 gene in EBV positive
pediatric patients with infectious mononucleosis
Autori
Rozman, Marija ; Židovec Lepej, Snježana
Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni
Skup
HIV Sibiu Dialogues V
Mjesto i datum
Bukurešt, Rumunjska, 26.05.2022. - 28.05.2022
Vrsta sudjelovanja
Predavanje
Vrsta recenzije
Međunarodna recenzija
Ključne riječi
EBV, BLLF1, infectious mononucleosis
Sažetak
Epstein-Barr virus (EBV, Human gammaherpesvirus 4) is an ubiquitous virus from a Herpesviridae family. It infects over 90% of people worldwide and causes malignancies such as Burkitt lymphoma, Hodgkin lymphoma and nasopharyngeal cancer. The majority of infections in children are asymptomatic but can present as infectious mononucleosis, most frequently among young adults. EBV infects naive B-lymphocytes, activates them and induces their proliferation. Virus attaches to B-lymphocytes through gp350 glycoprotein which interacts with complement receptor 2 (CR2) on their surface. In this study, the variability of BLLF1 gene that codes for gp350 glycoprotein was analysed among pediatric patients with infectious mononucleosis
Izvorni jezik
Engleski
