Naslov
Psoriasis vulgaris as a diagnostic problem in a patient with myasthenia gravis. Case report.
(Psoriasis vulgaris as a diagnostic problem in a patient with m yasthenia gravis. Case report.)

Autori
Bukvić-Mokos, Zrinka ; Marinović, Branka ; Dobrić, Ivan ; Basta-Juzbašić, Aleksandra ; Lakoš-Jukić, Ines ; Čeović, Romana.

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, stručni

Izvornik
Annales de dermatologie et de venereologie. Book II.Poster abstracts / Lorette, G. - Pariz : Masson, 2002

Skup
20th Word Congress of Ddermatology

Mjesto i datum
Pariz, Francuska, 01.07.2002. - 05.07.2002

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
psoriasis vulgaris; myasthenia gravis; diagnosis

Sažetak
A 51-year-old women suffered from myasthenia gravis for 20 years presented with psoriasiform, mildly infiltrated erythematosquamous plaques on her extremities and the upper part of her back, associated with tiredness and general malaise. First histological analysis could not confirm psoriasis vulgaris. The patient had undergone the UVB phototherapy with no improvement. Laboratory tests revealed positive antinuclear antibodies (ANA) in a titer 1:2, 560 and positive extractable nuclear antigens (ENA). According to these parameters, clinical findings and the course of the disease (photosensitivity), differential diagnosis included subacute lupus erythematosus. This was not confirmed by a second histological analysis (nonspecific inflammatory changes).Direct immunofluorescence of the affected skin showed linear deposits of C3 in the basement membrane zone and nuclear deposits of IgA in the epidermis. HLA-B8 was detected. Finally, third biopsy revealed the histological findings typical for psoriasis vulgaris.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

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