Naslov
Individual participant data meta-analysis to compare EPDS accuracy to detect major depression with and without the self-harm item

Autori
Qiu, Xia ; Wu, Yin ; Sun, Ying ; Levis, Brooke ; Tian, Jizhou ; Boruff, Jill T. ; Cuijpers, Pim ; Ioannidis, John P. A. ; Markham, Sarah ; Ziegelstein, Roy C. ; Vigod, Simone N. ; Benedetti, Andrea ; Thombs, Brett D. ; the DEPRESsion Screening Data (DEPRESSD) EPDS Group

Kolaboracija
DEPRESSD Collaboration

Izvornik
Scientific reports (2045-2322) 13 (2023); 4026, 12

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Depressive disorders ; Diagnostic interviews ; Individual participant data meta-analysis ; Major depression ; self-harm ; suicidality

Sažetak
Item 10 of the Edinburgh Postnatal Depression Scale (EPDS) is intended to assess thoughts of intentional self-harm but may also elicit concerns about accidental self-harm. It does not specifically address suicide ideation but, nonetheless, is sometimes used as an indicator of suicidality. The 9-item version of the EPDS (EPDS- 9), which omits item 10, is sometimes used in research due to concern about positive endorsements of item 10 and necessary follow-up. We assessed the equivalence of total score correlations and screening accuracy to detect major depression using the EPDS-9 versus full EPDS among pregnant and postpartum women. We searched Medline, Medline In-Process and Other Non-Indexed Citations, PsycINFO, and Web of Science from database inception to October 3, 2018 for studies that administered the EPDS and conducted diagnostic classification for major depression based on a validated semi-structured or fully structured interview among women aged 18 or older during pregnancy or within 12 months of giving birth. We conducted an individual participant data meta-analysis. We calculated Pearson correlations with 95% prediction interval (PI) between EPDS-9 and full EPDS total scores using a random effects model. Bivariate random-effects models were fitted to assess screening accuracy. Equivalence tests were done by comparing the confidence intervals (CIs) around the pooled sensitivity and specificity differences to the equivalence margin of δ = 0.05. Individual participant data were obtained from 41 eligible studies (10, 906 participants, 1407 major depression cases). The correlation between EPDS-9 and full EPDS scores was 0.998 (95% PI 0.991, 0.999). For sensitivity, the EPDS-9 and full EPDS were equivalent for cut- offs 7–12 (difference range − 0.02, 0.01) and the equivalence was indeterminate for cut-offs 13–15 (all differences − 0.04). For specificity, the EPDS-9 and full EPDS were equivalent for all cut- offs (difference range 0.00, 0.01). The EPDS-9 performs similarly to the full EPDS and can be used when there are concerns about the implications of administering EPDS item 10.

Izvorni jezik
Engleski

Znanstvena područja
Psihologija

POVEZANOST RADA