Naslov
Colorectal cancer - pathohistological standards

Autori
Šitić, Sanda ; Milković-Periša, Marija ; Bobuš- Kelčec, Iva ; Silovski, Tajana ; Silovski, Hrvoje ; Orešić, Tomislav

Izvornik
Libri Oncologici : Croatian Journal of Oncology (2584-3826) 41 (2013); 59-64

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, pregledni rad, znanstveni

Ključne riječi
colorectal cancer, TNM classification, personalized oncology

Sažetak
Colorectal carcinoma is the third most common cancer site in Croatia, according to the data published by the The Croatian National Cancer Registry. In the last decade, the knowledge about pathogenesis and molecular background of colorectal carcinoma has increased dramatically. More than 90% of colorectal carcinomas are adenocarcinomas originating from epithelial cells of the colorectal mucosa. Tumor staging is the most important prognostic predictor of clinical outcome for patients with colorectal carcinoma. The TNM classification has nowdays replaced other classification systems (Dukes, Astler-Coller) and serves as golden standard in everyday practise.In 2012, 5th Croatian Congress for Pathology resulted in uniform standard for pathologic reporting for all cancer sites. The future for colorectal cancer prognosis and therapy is to discover new molecular subtypes of colorectal cancer which represents the future of personalized oncology and will guide drug- development strategies.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti, Kliničke medicinske znanosti

POVEZANOST RADA