Naslov
Immune-mediated diseases after coronavirus disease 2019 vaccination: rare but important complication

Autori
Zagorec, Nikola ; Horvatić, Ivica ; Šenjug, Petar ; Horaček, Matija ; Galešić Ljubanović, Danica ; Galešić, Krešimir

Izvornik
Croatian medical journal (0353-9504) 63 (2022), 4; 389-393

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
COVID-19 vaccine ; IgA nephropathy ; Vasculitis

Sažetak
Ince the beginning of mass vaccination against coronavirus disease 2019 (COVID-19), vaccine- linked immunemediated diseases have been increasingly reported. The development of these diseases after COVID-19 vaccination may be attributed to the mechanisms of molecular mimicry and cross-reactivity between the viral spike protein and self-antigens. The most frequent vaccine-linked glomerular disease is immunoglobulin A nephropathy (IgAN). Cutaneous vasculitis has also been reported after COVID-19 vaccination. In both diseases, deposition of immune complexes activates the inflammatory response with end-organ damage. We report on a case of de novo IgAN in a young man and a case of severe cutaneous vasculitis in a 68- year-old woman, both after the second dose of Pfizer- BioNTech COVID-19 vaccine

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA