Naslov
Factors contributing to the duration of hospitalisation of patients with bacterial cellulitis

Autori
Mudrovčić, Monika ; Lukić, Ljiljana ; Puljiz, Maša ; Puljiz, Ivan

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Skup
30th ECCMID 2020

Mjesto i datum
Pariz, Francuska, 18.04.2020. - 21.04.2020

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
Hospitalization ; bacterial celullitis

Sažetak
Background: Bacterial cellulitis (BC) presents a therapeutic challenge. The optimal choice of antibimicrobial agent and duration of treatment for BC continue to be heavily debated. Our aim was to analyze risk factors and treatment regimens associated with a prolonged hospital stay. Materials/methods: We conducted a retrospective analysis of data from our cohort of 255 patients admitted to our university hospital from January 1st 2018 to December 31st 2018 with BC as the primary diagnosis. Statistical evaluation was done using Student’s t-test and ANOVA where appllicable. Results: The mean duration of hospital stay for all patients was 11, 2 days. The factors we found to be associated with a prolonged hospital stay were acute kidney injury at admission ; cardiac decompensation at admission ; the clinical observation that the patient appears unwell at admission ; a history of cardiovascular disease ; as well as chronic venous insufficiency. Age >65 years was also associated with a significantly longer hospital stay, as was identification of pathogens in a skin swab. Patients with no determinable gateway for infection had a significantly shorter hospital stay. We observed no signicant difference in the duration of hospitalization for patients with other comorbidities ; neither was there any relation of CRP levels at admission or highest documented axillary temperature to length of hospital stay. Cefazolin was the most commonly used antibiotic in our sample (45, 1% patients) and was associated with the shortest hospital stay, significantly shorter than cloxacillin or clindamycin (the second and third most commonly used monoterapy agents). Patients treated with monotherapy had a significantly shorter hospital stay than those initially treated with multiple antibiotics. Conclusions: The most significantly prolonged hospital stay was observed in patients with a toxic appearance and end organ damage at admission. Based on our data, cefazolin was the antibiotic associated with the shortest hospital stay. Patients recieving combined antimicrobial therapy were observed to have a prolonged clinical course, but this can likely be attributed to these patients having a more complex presentation.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA