Naslov
Mikrosfere kao dostavljači lijeka pri liječenju tumora kosti
(Microspheres as drug delivery systems for bone tumour treatment)

Autori
Lončarević, Andrea ; Rogina, Anamarija

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, neobjavljeni rad, znanstveni

Skup
Kompozitni biomaterijali u tkivnom inženjerstvu (Composite materials for bone tissue engineering application)

Mjesto i datum
Zagreb, Hrvatska, 26.09.2022

Vrsta sudjelovanja
Predavanje

Vrsta recenzije
Nije recenziran

Ključne riječi
kitozan ; mikrosfere ; antitumorski lijek ; metalni ioni ; kompleks
(chitosan ; microspheres ; antitumor drug ; metal ions ; complex)

Sažetak
Microspheres are considered promising tools as drug delivery systems for bone tumor treatment. In the lecture were presented two different methods of the preparation of microspheres: emulsion w/o and electrospraying. Also, the latest research on chitosan-based material preparation for application in bone engineering was presented. The focus was on the natural polymer chitosan, which is biocompatible, biodegradable, and non-toxic. Furthermore, chitosan possesses an ability to complex with metal ions, such as copper (II) and zinc (II) ions, which makes it a promising material for drug delivery. In the lecture were highlighted challenges in the determination of optimal process parameters and procedures for the preparation of chitosan-based complex microspheres, as well as challenges during a drug loading and release process.

Izvorni jezik
Hrvatski

Znanstvena područja
Kemija, Kemijsko inženjerstvo, Temeljne tehničke znanosti, Interdisciplinarne tehničke znanosti

POVEZANOST RADA