Naslov
The urgent need to recognize and properly address prenatal-onset group B Streptococcus disease

Autori
Costa, Natália Silva ; Oliveira, Laura Maria Andrade Oliveira ; Meštrović, Tomislav ; Obiero, Christina W ; Lee, Shui Shan ; Pinto, Tatiana Castro Abreu

Izvornik
International journal of infectious diseases (1201-9712) 124 (2022); 168-170

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, uvodnik, znanstveni

Ključne riječi
Streptococcus agalactiae ; Group B Streptococcus ; prenatal-onset streptococcal disease

Sažetak
Group B Streptococcus (GBS) neonatal infections can be classified according to the timing of symptoms’ onset and mode of microorganism acquisition into early- and late-onset disease. Early-onset GBS disease occurs up to 7 days after birth and is usually associated with vertical intrapartum acquisition. Late-onset disease occurs between 7 and 90 days after birth and is due to horizontal postpartum acquisition from a variety of sources, including the hospital environment, the mother or other caregivers, or by breastfeeding. A much less well-known form of GBS infection is the prenatal-onset GBS disease (POGBS), which occurs any time before delivery due to in utero acquisition. Bacteria can reach the fetus due to an ascending infection from the vagina, even in the presence of intact membranes. GBS colonizes asymptomatically the vaginal tract of 18% of pregnant women worldwide, varying from 10% to 40% according to the geographic region. POGBS can lead to miscarriage, stillbirth, early rupture of membranes and preterm labor.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti, Javno zdravstvo i zdravstvena zaštita

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