Naslov
Effect of Mushroom Culture Filtrates on inhibition of Mycotoxins Pruduced by Aspergillus flavus and Aspergillus carbonarius

Autori
Lončar, Jelena ; Reverberi, Massimo ; Cescutti ; Motola, Alice ; Zjalić, Slaven

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Book of abstracts 7th Croatian Congress of Microbiology with International Participation / Sviličić Petrić, Ines ; Leboš Pavunc, Andreja ; Šantić, Marina ; Kifer, Domagoj - Zagreb : Hrvatsko mikrobiološko društvo, 2022, 65-65

ISBN
978-953-7778-18-7

Skup
7th Croatian Congress of Microbiology

Mjesto i datum
Sveti Martin na Muri, Hrvatska, 24.05.2022. - 27.05.2022

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
mycotoxin, biocontrol, mushroom polysaccharides

Sažetak
Mycotoxins are low-molecular-weight secondary metabolites synthesized by some filamentous fungi, toxic to animals and humans. As a contaminant they can be found on different feed and food stuff, especially in cereal grains. The widespread and indiscriminate use of chemicals in the prevention of fungal colonization has led to detrimental ecological effects and environmental pollution. Thus, there is a need for the development of new alternative, safer and more environmentally friendly strategies to tackle the worldwide problem of mycotoxin contamination. It has been reported that extracts from two mushroom species, Lentinula edodes and Trametes versicolor showed the ability to provide a long- lasting inhibition of aflatoxin (AF) synthesis and T. versicolor polysaccharides also inhibited a synthesis of ochratoxin A (OTA). To verify whether the other mushrooms produce metabolites able to control both AF and OTA synthesis, a wide screening of 42 isolates of different ligninolytic mushrooms were assayed for their ability to inhibit the synthesis of OTA in Aspergillus carbonarius AFB1 in Aspergillus flavus, respectively. The results showed that 23 strains produce metabolites able to inhibit the synthesis of OTA by >20%, and 32 strains that produced metabolites that inhibited AFB1 by >30%. Only two strains, Trametes versicolor strain TV117 and Schizophyllum commune strain S.C. Ailanto, produced metabolites able to significantly inhibit (>90%) the synthesis of both mycotoxins. Preliminary results suggest that the mechanism of efficacy of the S. commune rough and semi-purified polysaccharides could be analogous to that found previously for TV117 polysaccharides (Tramesan), by enhancing the antioxidant response in the target fungal cells. Thus, S. commune’s exopolysaccharides should be characterized, and their structure defined and compared to those of Tramesan to establish whether there are some determinative structural characteristics of polysaccharides which make them active in aflatoxin inhibition

Izvorni jezik
Engleski

Znanstvena područja
Biotehnologija

POVEZANOST RADA