Naslov
Impact of polypharmacy on frequency of falls and hospitalizations in older adults: Croatian study from the EUROAGEISM H2020 project

Autori
Držaić, Margita ; Kummer, Ingrid ; Bužančić Iva ; Marušić, Maja ; Šepetavc, Martina ; Bošković, Andrea ; Brkić, Jovana ; Ortner Hadžiabdić Maja ; Fialova, Daniela

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
49th ESCP virtual symposium on clinical pharmacy 19.10.2021–21.10.2021 Clinical pharmacy, working collaboratively in mental health care / - : International Journal of Clinical Pharmacy, 2021, 1736-1801

Skup
49th ESCP virtual symposium on clinical pharmacy

Mjesto i datum
Prag, Češka Republika, 19.10.2021

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
polypharmacy, falls, older adults, EuroAgeism

Sažetak
Background and Objective: The aim of this study was to explore the association between number of prescribed medications and their impact on frequency of falls and hospitalizations in community-residing older adults. Method: This observational, cross-sectional study was conducted as part of the EUROAGEISM H2020 ESR 7 project. Presented data are preliminary and include 84 adults aged C 65 years who attended three community pharmacies in the City of Zagreb. Data were collected using structured, standardized questionnaire developed for the purpose of the EUROAGEISM H2020 project. Descriptive and inferential statistical methods were applied to analyse data using IBM SPSS v 20. Main outcome measures: Association between number of prescribed medications and the incidence of falls and hospitalizations in the last 12 months. Results: Final analysis included 84 participants (67.9% female ; median age 73 (IQR 68–80)). Every participant used on average 5, 62±2, 916 prescribed medications, while polypharmacy (5+medications) was identified in 51 (60, 7%) of them. Use of at least one medication from the benzodiazepine drug class was observed in 32 (38, 1%) of the participants, with females using them statistically significantly more often than males (V2 (1) = 4, 251, p\0, 05). Of the total number of participants, 57 (67, 9%) experienced a fall in the past, of which 17 (20, 2%) in the last 12 months. Female participants have fallen statistically significantly more often in the past than males (V2 (1) = 4, 673, p\ 0, 05). Only 12 (14.3%) participants were hospitalized in the last 12 months, while men were statistically significantly more often hospitalized than women (V2 (1) = 4, 403, p\ 0, 05). A positive trend was observed showing that higher number of medications were prescribed in participants who fell (6.00 ± 2.716 vs. 5.52 ± 2.976 ; p[ 0.05) or were hospitalized (6.58 ± 2.937 vs. 5.46 ± 2, 902 ; p[ 0.05) in the last 12 months, however, the statistical significance was not confirmed. Conclusion: This study provides preliminary results regarding association between number of medications prescribed and frequency of falls and hospitalizations in community-residing older adults in the City of Zagreb and indicates the importance of pharmacotherapy optimisation in this vulnerable age group. Grant support: EuroAgeism H2020 MSCF-ITN-764632, Inomed NO.CZ.02.1.01/0.0/0.0/18_069/0010046, Progress Q42- Faculty of Pharmacy, Charles University, START/MED/093 CZ.02.2.69/0.0/0.0/ 19_073/0016935, SVV 260551 and ICARE4OLD H2020 -96534.

Izvorni jezik
Engleski

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