Pregled bibliografske jedinice broj: 1249772
Bioprospecting of Targeted Phenolic Compounds of Dictyota dichotoma, Gongolaria barbata, Ericaria amentacea, Sargassum hornschuchii and Ellisolandia elongata from the Adriatic Sea Extracted by Two Green Methods
Bioprospecting of Targeted Phenolic Compounds of Dictyota dichotoma, Gongolaria barbata, Ericaria amentacea, Sargassum hornschuchii and Ellisolandia elongata from the Adriatic Sea Extracted by Two Green Methods // Marine drugs, 21 (2023), 2; 97, 14 doi:10.3390/md21020097 (međunarodna recenzija, članak, znanstveni)
CROSBI ID: 1249772 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Bioprospecting of Targeted Phenolic Compounds of
Dictyota dichotoma, Gongolaria barbata, Ericaria
amentacea, Sargassum hornschuchii and Ellisolandia
elongata from the Adriatic Sea Extracted by Two
Green Methods
Autori
Castillo, Aly ; Celeiro, Maria ; Lores, Marta ; Grgić, Kristina ; Banožić, Marija ; Jerković, Igor ; Jokić, Stela
Izvornik
Marine drugs (1660-3397) 21
(2023), 2;
97, 14
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni
Ključne riječi
Adriatic Sea macroalgae ; polyphenols ; matrix solid-phase dispersion ; ultrasound-assisted extraction ; green chemistry
Sažetak
The content of bioactive compounds in four brown and one red algae from the Adriatic Sea (Dictyota dichotoma, Gongolaria barbata, Ericaria amentacea, Sargassum hornschuchii and Ellisolandia elongata) is explored. The efficiency of two different extraction methods viz. ultrasound-assisted extraction (UAE) and matrix solid-phase dispersion (MSPD) to obtain the extracts rich in phenolic compounds was compared. The effect of the extraction solvent to modulate the phenolic profile was assessed. In general, the mixture ethanol/water in an isovolumetric proportion showed the best results. The total phenolic content (TPC) and antioxidant activity (AA), as well as the individual polyphenolic profile, were evaluated for five target algae. TPC values ranged between 0.2 mg GAE/g (for E. elongata) and 38 mg GAE/g (for S. hornschuchii). Regarding the quantification of individual polyphenols by liquid chromatography-tandem mass spectrometry (LC-MS/MS) analysis, the presence of a high number of hydroxybenzoic acid derivatives (mainly of 3- and 4-hydroxybenzoic acids) in all species was noted. In G. barbata their concentrations reached up to 500 mg/kg. IC50 values (ABTS assay) ranged between 44 mg/L (for S. hornschuchii) and 11, 040 mg/L (for E. elongata). This work contributes to the in- depth characterization of these little-explored algae, showing their potential as a natural source of phenolic compounds.
Izvorni jezik
Engleski
Znanstvena područja
Farmacija
POVEZANOST RADA
Projekti:
EK-KF-KK.01.1.1.01.0002 - Bioprospecting Jadranskog mora (Jerković, Igor; Dragović-Uzelac, Verica; Šantek, Božidar; Čož-Rakovac, Rozelinda; Kraljević Pavelić, Sandra; Jokić, Stela, EK ) ( CroRIS)
Ustanove:
Kemijsko-tehnološki fakultet, Split,
Prehrambeno-tehnološki fakultet, Osijek
Citiraj ovu publikaciju:
Časopis indeksira:
- Web of Science Core Collection (WoSCC)
- Science Citation Index Expanded (SCI-EXP)
- SCI-EXP, SSCI i/ili A&HCI
- Scopus
- MEDLINE