Naslov
Neuroendocrine Tumors of Larynx – Two Case Reports and Literature Review

Autori
Carić, Tomislav ; Bilić, Mario ; Kovač, Lana ; Prgomet, Drago ; Kovačić, Jelena, Topić Grahovac, Iva ; Hutinec, Zdenka

Izvornik
Collegium antropologicum (0350-6134) 36 (2012); 173-178

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
neuroendocrine tumors, laryngeal neoplasms, therapy

Sažetak
Neuroendocrine tumors (NET) of the larynx are rare and heterogenous group, with much confusion about nature and classification of these neoplasms in the past. Diagnosis is based primarily on light microscopy and confirmed by immunohistochemistry and electron microscopy. A classification in 4 different types ; paraganglioma, typical carcinoid, atypical carcinoid and small cell neuroendocrine carcinoma (SCNC) is a current consensus. Thorough diagnostic and a proper classification of neuroendocrine neoplasms are of paramount importance – prognosis and treatment differ significantly. We present two cases: 63-year old patient with SCNC of the larynx and a 53-year old patient with atypical carcinoid of the larynx. OctreoScan is useful tools for diagnostics and follow up of the patients and it is predictive for effectiveness of octreotide therapy.

Izvorni jezik
Engleski

Znanstvena područja
Biotehnologija u biomedicini (prirodno područje, biomedicina i zdravstvo, biotehničko područje)

POVEZANOST RADA