Naslov
(Reactive) Eccrine syringofibroadenoma with foci of squamous cell carcinoma in situ: a case report

Autori
Franin, Ivan ; Regović Džombeta, Tihana ; Krušlin, Božo ; Tomas, Davor

Izvornik
Acta Dermatovenerologica Croatica (1330-027X) 29 (2021), 4; 224-227

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, stručni

Ključne riječi
eccrine syringofibroadenoma ; squamous cell carcinoma in situ ; immunohistochemistry

Sažetak
We describe a rare case of an eccrine syringofibroadenoma with a foci of squamous cell carcinoma in situ, which has to best of our knowledge been reported only twice in the English literature. An excisional biopsy of an elevated, lobular tumor of the lower leg in an 86-yearold male patient was performed. Histologic examination revealed a tumor consisting of anastomosing strands of epithelial cells originating from the epidermis, occasionally showing ductal eccrine differentiation. Foci of squamous cell carcinoma in situ were observed within the described lesion. The diagnosis of eccrine syringofibroadenoma with squamous cell carcinoma in situ was established. Eccrine syringofibroadenoma is a rare lesion, mostly considered to be a reactive process arising secondarily in association with other cutaneous diseases such as dermatoses or neoplasms, although some researchers do not exclude the possibility that it is a primary neoplasm with a potential for malignant transformation.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA