Pregled bibliografske jedinice broj: 1246095
Helicobacter pylori antibiotic resistance: data from the European registry on H. pylori management (HP-EUREG)
Helicobacter pylori antibiotic resistance: data from the European registry on H. pylori management (HP-EUREG) // United European Gastroenterology Journal 8(2020)S8
Beč, Austrija; online, 2020. str. 257-258 (poster, međunarodna recenzija, sažetak, stručni)
CROSBI ID: 1246095 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Helicobacter pylori antibiotic resistance: data
from the European registry on H. pylori management
(HP-EUREG)
Autori
Bujanda L., Nyssen O.P., Cosme A., Bordin D.S., Tepeš B., Pere-Aisa A., Vaira D., Caldas Álvarez M., Castro-Fernandez M., Lerang F., Leja M., Rodrigo L., Rokkas T., Kupcinskas L., Perez-Lasala J., Jonaitis L., Shvets O., Gasbarrini A., Simsek H., Axon A.T.R., Buzas G.M., Machado J.C., Niv Y., Boyanova L., Goldis A., Lamy V., Tonkić Ante, Marlicz W., Beglinger C., Venerito M., Bytzer P., Capelle L.G., Milosavljevic T., Veijola L.I., Molina Infante J., Vologhzanina L., Fadeenko G., Ariño I., Fiorini G., Resina E., Muñoz R., Puig I., Megraud F., O’ Morain C., Gisbert J.P.
Kolaboracija
Hp-EuReg Investigators
Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, stručni
Izvornik
United European Gastroenterology Journal 8(2020)S8
/ - , 2020, 257-258
Skup
28th United European Gastroenterology Week
Mjesto i datum
Beč, Austrija; online, 11.10.2020. - 13.10.2020
Vrsta sudjelovanja
Poster
Vrsta recenzije
Međunarodna recenzija
Ključne riječi
Helicobacter pylori ; antibiotic resistance
Sažetak
Introduction: Antibiotic resistance is the major factor affecting our ability to cure Helicobacter pylori infection. Understanding the different H. pylori antibiotic resistances could be the key to improve treatment effectiveness. Aims & Methods: To evaluate the H. pylori antibiotic resistance both prior and after one or several eradication treatments, in order to provide the most appropriate recommendations for the eradication of H. pylori. International multicenter prospective non-interventional European Regis-try on H. pylori Management (Hp- EuReg) aiming to evaluate the decisions and outcomes of H. pylori infection by European gastroenterologists. Infected adult patients diagnosed with culture and with a result of the antibiotic resistance test registered at AEG- REDCap e-CRF from 2013 to 2019. Per-protocol (PP) analysis was performed. The antibiotic bacterial resistances were described by treatment line. Results: A total of 32, 447 patients were included, and culture was performed in 3, 474 (11%). In naïve patients, 21% reported single clarithromycin resistance, and 11% dual (clarithromycin and metronidazole) resistance. Antibiotic resistance increased markedly from the first treatment, reaching over 37% dual resistance in second-line treatment. Conclusion: In Europe, culture testing to determine antibiotic resistance against H. pylori is scarce. H. pylori single clarithromycin resistance remains high (>15%) in all treatment lines, and greater than 20% in naïve patients. Dual or triple resistances are frequent and increase remarkably after the first treatment failure. Resistance to amoxicillin or tetracycline is exceptional.
Izvorni jezik
Engleski
Znanstvena područja
Kliničke medicinske znanosti
