Naslov
Differences of Helicobacter pylori diagnostics and treatment in the elderly and non-elderly populations: data from European registry on H. pylori management (HP-EUREG)

Autori
Jonaitis, P. ; Kupcinskas, J. ; Pérez-Aísa, Á. ; Vaira, D. ; Tepes, B. ; Bordin, D. ; Bujanda, L. ; Denkovski, M. ; Lanas, A. ; Leja, M. ; Babayeva, G. ; Lerang, F. ; Tonkić, Ante ; Nyssen, O. P. ; Moreira, L. ; Puig, I. ; Mégraud, F. ; O’Morain, C. ; Gisbert, J. P. ; Jonaitis, L.

Kolaboracija
Hp-EuReg Investigators

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, stručni

Izvornik
35th International Workshop on Helicobacter & Microbiota in Inflammation & Cancer / - , 2022, 42-43

Skup
International Workshop on Helicobacter and Microbiota in Inflammation and Cancer

Mjesto i datum
Glasgow, Ujedinjeno Kraljevstvo, 08.09.2022. - 10.09.2022

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
Helicobacter pylori

Sažetak
Objective: There might be some peculiarities in the diagnostics and treatment of H. pylori in the elderly population. The aim of the study was to compare the demographics, diagnostics and treatments of H. pylori infection in the elderly (≥60 years) and non-elderly (18-59 years). Patients and Methods: European multicenter registry of H. pylori infection management (Hp- EuReg) collecting data until 2022. Subjects were divided into the non-elderly (18-59 years) and elderly (≥60 years) groups. Results: Results are presented in Table 1. 14, 467 elderly and 34, 994 non-elderly patients were included. Elderly patients had more concurrent medications and drug allergies (p<0.05). There were significant differences in most of main H. pylori diagnostic tests before and after the treatment between groups. The duration of first- line treatment in the elderly and non-elderly was 7 days in 14% and 12%, 10 days in 50% and 49%, and 14 days in 36% and 40%, respectively, (p<0.05 for all groups), but no significant differences in prescribed PPI doses were found. In second-line treatment, no differences in treatment durations were reported ; however, low-dose PPIs were more frequently prescribed in the elderly and high-dose PPIs in the non-elderly. No differences were found in overall treatment compliance, but the AEs rate was lower in the elderly (p<0.05). Conclusions: Age group differences were reported in concurrent medications, drug allergies, AEs and prescribed regimens both in first- and second-line treatments. Treatment compliance was similar between groups.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA