Naslov
Rapid removal of tolperisone from waters by application of heterogeneous photocatalysis

Autori
Šojić Merkulov, Daniela ; Bognar, Szabolcs ; Velebit, Branko ; Despotović, Vesna ; Finčur, Nina ; Putnik, Predrag

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Book of Abstracts of the 2nd International Conference on Advanced Production and Processing publishes abstracts from the following fields: Innovative Food Science and Bioprocesses, Nutraceuticals and Pharmaceuticals, Sustainable Development, Chemical and Environmental Engineering, Materials Design and Applications, Petroleum Refining and Production / Šereš, Zita - Novi Sad : Tehnološki fakultet Univerziteta u Novom Sadu, 2022, 222-222

ISBN
978-86-6253-160-5

Skup
2nd International Conference on Advanced Production and Processing

Mjesto i datum
Novi Sad, Serbia, 20.10.2022. - 22.10.2022

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
Heterogeneous photocatalysis ; Tolperisone ; Chemometric analysis

Sažetak
Tolperisone hydrochloride (TLP) is a piperidine derivative and belongs to the group of muscle relaxant pharmaceuticals. TLP affects spasticity through interaction with upper motor neurons (central acting muscle relaxants). It is commercially available under different trademarks (e.g. Biocalm®, Muscodol®, Mydeton®, Mydocalm, etc.) and used in various treatments of rheumatological, orthopedic and traumatic neurological disorders. TLP is extremely hazardous for water and should not be allowed to reach the ground water, water course or sewage system, even in small quantities. Moreover, it is dangerous to the drinking water if even extremely small quantities leak into the ground. Advanced oxidation processes are proved to be capable as method that may remove up to 100% of various drugs from waters. Heterogeneous photocatalysis is based on the application of different semiconductors as photocatalysts (such as TiO2, ZnO, etc.). This technology has key advantage of including operation at ambient conditions with catalyst that are inexpensive, commercially available in various crystalline forms, with particle characteristics and photochemically stable. Accordingly, for removal of TLP from water, the photocatalytic experiments in the presence of two types of photocatalyst, namely TiO2 and ZnO with simulated solar irradiation and UV light were carried out. The findings obtained by using chemometric analysis showed that the complete TLP removal can be reached using TiO2 as photocatalyst (1.0 mg/mL), after 60.83 min of UV irradiation. To confirm removal of TLP from samples and to detect the eventual photodegradation intermediates, LC– ESI–MS analysis was done.

Izvorni jezik
Engleski

Znanstvena područja
Kemija, Kemijsko inženjerstvo, Poljoprivreda (agronomija), Biotehnologija

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