Naslov
Preoperative assessment of ovarian tumors by CA 125 measurement and transvaginal color Doppler ultrasound

Autori
Kupešić, Sanja ; Vujisić, Sanja ; Kurjak, Asim ; Mihaljević, Daria ; Radošević, Sanja

Izvornik
Acta medica Croatica (1330-0164) 56 (2002); 3-10

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
CA 125; ovarian tumors; color Doppler

Sažetak
The accuracy of combined use of serum CA 125 and transvaginal color Doppler for preoperative assessment of ovarian lesions in premenopausal patients was evaluated. Seventy-six ovarian lesions were analyzed the day before surgery using transvaginal color Doppler ultrasound. On the same day, serum CA 125 was measured in each patient. A novel index is proposed for the detection of ovarian malignancy combining resistance index (RI) obtained from newly formed vessels within the ovarian lesion and serum CA 125 level: (RI/CA 125) x 100. Values below the cut-off value of 1.5 were associated with a high risk of ovarian malignancy. Assessment of ovarian lesions by the novel index had a sensitivity and specificity of 94.44% and 100%, while positive and negative predictive values were 100% and 98.31%, respectively. The best prediction of ovarian malignancy was achieved by a combined use of transvaginal color Doppler ultrasound and serum CA 125 in the form of index: (RI/CA 125) x 100.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

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