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Pregled bibliografske jedinice broj: 1237683

N,N′-Di-Boc-2H-Isoindole-2-carboxamidine—First Guanidine-Substituted Isoindole

Štrbac, Petar; Briš, Anamarija; Margetić, Davor
N,N′-Di-Boc-2H-Isoindole-2-carboxamidine—First Guanidine-Substituted Isoindole // Molecules, 27 (2022), 24; 8954, 12 doi:10.3390/molecules27248954 (međunarodna recenzija, članak, znanstveni)

CROSBI ID: 1237683 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
N,N′-Di-Boc-2H-Isoindole-2-carboxamidine—First Guanidine-Substituted Isoindole

Autori
Štrbac, Petar ; Briš, Anamarija ; Margetić, Davor

Izvornik
Molecules (1420-3049) 27 (2022), 24; 8954, 12

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
cycloaddition ; Diels–Alder reaction ; heterocycles ; organic synthesis ; indoles ; DFT calculations

Sažetak
Synthesis of N, N′-Di-Boc-2H-isoindole-2-carboxamidine, the first representative of isoindoles containing guanidine functionality, was carried out. The cycloaddition reactivity of this new Diels–Alder heterodiene was studied and the title compound was employed as a cycloaddition delivery reagent for guanidine functionality. Higher reactivity was found in comparison with the corresponding pyrrole derivative. Substitution with fluorine or guanidine functionality does not change the reactivities of isoindoles, and these findings are in good accord with computational results.

Izvorni jezik
Engleski

Znanstvena područja
Kemija



POVEZANOST RADA

Projekti:
HRZZ-IP-2018-01-3298 - Cikloadicijske strategije prema policikličkim gvanidinima (CycloGu) (Margetić, Davor, HRZZ - 2018-01) ( CroRIS)

Ustanove:
Institut "Ruđer Bošković", Zagreb

Profili:

Avatar Url Anamarija Briš (autor)

Avatar Url Davor Margetić (autor)

Avatar Url Petar Štrbac (autor)

Poveznice na cjeloviti tekst rada:

doi www.mdpi.com fulir.irb.hr

Citiraj ovu publikaciju:

Štrbac, Petar; Briš, Anamarija; Margetić, Davor
N,N′-Di-Boc-2H-Isoindole-2-carboxamidine—First Guanidine-Substituted Isoindole // Molecules, 27 (2022), 24; 8954, 12 doi:10.3390/molecules27248954 (međunarodna recenzija, članak, znanstveni)
Štrbac, P., Briš, A. & Margetić, D. (2022) N,N′-Di-Boc-2H-Isoindole-2-carboxamidine—First Guanidine-Substituted Isoindole. Molecules, 27 (24), 8954, 12 doi:10.3390/molecules27248954.
@article{article, author = {\v{S}trbac, Petar and Bri\v{s}, Anamarija and Margeti\'{c}, Davor}, year = {2022}, pages = {12}, DOI = {10.3390/molecules27248954}, chapter = {8954}, keywords = {cycloaddition, Diels–Alder reaction, heterocycles, organic synthesis, indoles, DFT calculations}, journal = {Molecules}, doi = {10.3390/molecules27248954}, volume = {27}, number = {24}, issn = {1420-3049}, title = {N,N′-Di-Boc-2H-Isoindole-2-carboxamidine—First Guanidine-Substituted Isoindole}, keyword = {cycloaddition, Diels–Alder reaction, heterocycles, organic synthesis, indoles, DFT calculations}, chapternumber = {8954} }
@article{article, author = {\v{S}trbac, Petar and Bri\v{s}, Anamarija and Margeti\'{c}, Davor}, year = {2022}, pages = {12}, DOI = {10.3390/molecules27248954}, chapter = {8954}, keywords = {cycloaddition, Diels–Alder reaction, heterocycles, organic synthesis, indoles, DFT calculations}, journal = {Molecules}, doi = {10.3390/molecules27248954}, volume = {27}, number = {24}, issn = {1420-3049}, title = {N,N′-Di-Boc-2H-Isoindole-2-carboxamidine—First Guanidine-Substituted Isoindole}, keyword = {cycloaddition, Diels–Alder reaction, heterocycles, organic synthesis, indoles, DFT calculations}, chapternumber = {8954} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE

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