Pregled bibliografske jedinice broj: 123481
HLA-B/HLA-C Region as a marker of psoriasis type I in Croatian patients
HLA-B/HLA-C Region as a marker of psoriasis type I in Croatian patients // European Journal of Immunogenetics, 29 (2002), 2. (podatak o recenziji nije dostupan, kongresno priopcenje, znanstveni)
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Naslov
HLA-B/HLA-C Region as a marker of psoriasis type I in Croatian patients
Autori
Grahovac, Blaženka ; Dražić, Vesna ; Pašić, Aida ; Bingulac-Popović, J
Izvornik
European Journal of Immunogenetics (0960-7420) 29
(2002), 2;
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, kongresno priopcenje, znanstveni
Ključne riječi
HLA typization; marker for psoriasis; psoriasis in Croatian patients
Sažetak
Psoriasis (PV) is a chronic skin disease strongly associated with several susceptibility genes. Recent genome - Wide linkage anlyses have identified a locus susceptibility to PV (PSOR 1), which is pad of HLA region (HLA-B/HLA-C) maped on chromosome 6 p 21.3. The aim of the suty was to indentify risk HLA alleles and haplotypes associated with type I PV according to the age on onset. Total 138 unrelated patients with type I PV (early onset < 40 years). Haplotype analyses revealed that early psoriasis onset (<20 years)is more significantly associated with B*13-Cw*0602 haplotype (p=0.006 for type Ia), than with B*57-Cv*0602 (p=0.0139 for type Ia).
Izvorni jezik
Engleski
Znanstvena područja
Farmacija
Citiraj ovu publikaciju:
Časopis indeksira:
- Current Contents Connect (CCC)
- Web of Science Core Collection (WoSCC)
- Science Citation Index Expanded (SCI-EXP)
- SCI-EXP, SSCI i/ili A&HCI
- Scopus
- MEDLINE
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