Naslov
Case report: Atypical anaphylactic reaction to Patent Blue V dye during breast cancer surgery

Autori
Misir Šitum, Stanka ; Korečić Zrinjščak, Iva ; Pečvarac, Maja ; Šoštar, Andrea ; Žaja, Ana ; Tot, Tea

Izvornik
Frontiers in oncology (2234-943X) 12 (2022); 979393, 4

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, prikaz, ostalo

Ključne riječi
anaphylactic reaction ; anesthesia ; breast cancer ; case report ; patent blue V dye

Sažetak
The most common causes of perioperative hypersensitive reactions are neuromuscular blocking drugs, latex, and antibiotics, although there are other more emerging causative agents. Allergic reactions to Patent Blue V (PBV) dye have been reported. Most of them are mild and presented with blue coloration of cutaneous plaque. The PBV dye is widely used in the identification of sentinel lymph nodes in patients with breast cancer and other malignancies. Here, we present a case of 33-year-old patient with carcinoma of the breast proposed for sentinel lymph node and skin- sparing mastectomy with severe, life-threatening anaphylaxis which occurred immediately after PBV dye was injected, with cardiopulmonal resuscitation and prolonged refractory hypotension. The patient was without previous exposure to PBV and signs of skin rash, erythema, or bronchospasm, making the diagnosis and management of such cases challenging. Skin tests were performed on all drugs used in premedication and induction of anesthesia and PBV showed positive at IDT of 1:10. Physicians must always think of possible adverse reaction to PBV and for the potential risk of anaphylactic reaction immediately after the dye is injected, during anesthesia and other procedures.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA