Naslov
Application of the Amniotic Membrane Extract (AMX) for the Persistent Epithelial Defect (PED) of the Cornea

Autori
Kordić, Rajko ; Popović Suić, Smiljka ; Jandroković, Sonja ; Kalauz, Miro ; Kuzman, Tomislav ; Škegro, Ivan ; Jukić, Tomislav

Izvornik
Collegium antropologicum (1848-9486) 37 Supplement 1 (2013), 1; 161-164

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Amniotic membrane extract ; persistent epithelial defect ; neurotrophic keratopathy

Sažetak
A lot of pathological conditions could provoke damaging of the innervations of the cornea and lead to persistent epithelial defect (PED). AMX is lyophilized preparation of amniotic membrane (AM), which contains biological components and efficacy of AM for treatment of the corneal surface defects. In processing all the substances essential for biological effects of AM are preserved (growth factors, neutrophins, interleukins, receptors, fibronectins and different types of collagen). A patient can apply AMX as eye drops by himself in his home, thus avoiding surgical procedure. We presented two patients with PED ; we treated them with eye drops of AMX, 2 drops every hour during day time. There was observed healing effect by reducing epithelial defect. Almost after a second day of application, and after 1-2 week period PED that persisted for weeks healed completely.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA