Naslov
MALNUTRITION AND COGNITIVE-MOTOR FUNCTION IN HEMODIALYSIS PATIENTS: ARE THEY RELATED?

Autori
Radic Josipa, Kovacic Vedran, Radic Mislav, Ljutic Dragan, Sain Milenka

Izvornik
Nephrology, dialysis, transplantation (0931-0509) 4 (2011); Supl 2, 1

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, kratko priopcenje, znanstveni

Ključne riječi
hemodialysis, malnutrition, cognitive function

Sažetak
INTRODUCTION AND AIMS: Cognitive impairment is a frequent phenomenon in end-stage renal disease patients on hemodialysis (HD) and has also been associated with a decreased quality of life in HD patients. Also, malnutrition is a common in these patients and is linked to increased morbidity and mortality and decreased quality of life. The aim of the study was to analyze influence of malnutrition on cognitive-motor function. METHODS: To evaluate whether malnutrition is associated with cognitive-motor functions a selected population of sixty-five (20 females, 45 males) adult patients on chronic (4.28±4.78 years) HD aged 57.84±12.28 years were investigated. Assessment of cognitive-motor functions was performed by Complex Reactiometer Drenovac (CRD series), a battery of computer generated psychological tests to measure simple visual discrimination of signal location (CRD-311), short-term memory (CRD-324), simple convergent visual orientation (CRD-21) and convergent thinking (CRD-11). Results of cognitive motor tests were given as total time of test solving (TT) and minimum time of test item solving (Tmin). Total ballast (TB) is representing “lost” time expressed as a sum of differences between Tmin and each of all other single task solving times. Higher CRD-series tests scores (TT, MT and TB measured in seconds) indicate poorer cognitive and motor performance (tests took longer to complete). To asses the nutritional status dialysis malnutrition score (DMS) were used. A lower DMS score denotes tendency towards a normal nutritional status and a higher score, however, is considered to be an indicator of the presence of malnutrition elements. RESULTS: There were significant correlations between DMS and TT of solving test CRD- 311(r=0.215, p= 0.042), test CRD-21 (r= 0.262, p= 0.020) and test CRD- 11(r= 0.244, p=0.034). Also, a significant correlations between DMS and TB for test CRD-311 (r=0.281, p= 0.012), test CRD-324 (r=0.239, p= 0.028) were found. Therefore, MT in test CRD- 21 and test CRD-11 were significantly correlated with DMS (r=0.227, p=0.038), (r=0.223, p= 0.048) respectively. Correlations between Dialysis Malnutrition Score (DMS) and cognitive-motor functions. Pearson´s Correlation coefficient p CRD_311_TT 0.215 0.042* CRD_311_MT 0.160 0.101 CRD_311_TB 0.281 0.012* CRD_324_TT 0.182 0.075 CRD_324_MT 0.035 0.390 CRD_324_TB 0.239 0.028* CRD_21_TT 0.262 0.020* CRD_21_MT 0.227 0.038* CRD_21_TB 0.204 0.055 CRD_11_TT 0.244 0.034* CRD_11_MT 0.223 0.048* CRD_11_TB 0.193 0.075 TMT_A 0.162 0.135 SDMT -0.159 0.145 * p<0.05 CONCLUSIONS: This study demonstrated that cognitive-motor perfomance and malnutrition are significantly correlated. Nutritional status and cognitive function are frequently ignored in manly dialysis centers, although simple methods of nutritional and cognitive assessment could have favourable impact of patient menagment and guality of life.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA